TO THE EDITOR: In their recent paper, Cornachione et al. (1) draw three major conclusions: 1) that cardiac myofibrils do not show static tension or residual force enhancement; 2) that static tension/residual force enhancement is directly related to titin isoforms; and 3) that static tension/residual force enhancement is not associated with titin-actin interactions. Here, I would like to point o...

Cells have the ability to actively sense their mechanical environment and respond to both substrate stiffness and stretch by altering their adhesion, proliferation, locomotion, morphology, and synthetic profile. In order to elucidate the interrelated effects of different mechanical stimuli on cell phenotype in vitro, we have developed a method for culturing mammalian cells in a two-dimensional ...

Volitional muscle contractions are used frequently in some combination with muscle stretching to promote muscle relaxation and to increase range of motion. In this study, muscle lengthening procedures were evaluated in the ankle plantar flexors. Four soleus muscle stretching procedures--static stretch (SS), hold relax (HR) (isometric plantar flexor contraction before stretch), agonist contract ...

this study was a clinical trial performed using consecutive method of samplind for 3.5 years in the physiotherapy clinic of Rafsanjan university of medocal sciences.the purpose of this research was to evaluate the effect of the ultrasound along with muscle stretch with ultrasound and muscle stretch along in the treatment of the myofascial trigger points(MTPs).one haundred and twenty patients wh...

Mechanical ventilation has been shown to cause ventilator-induced lung injury (VILI), probably by overdistending or stretching the lung. Hyaluronan (HA), a component of the extracellular matrix (ECM), in low molecular weight (LMW) forms has been shown to induce cytokine production. LMW HA is produced by hyaluronan synthase 3 (HAS 3). We found that HAS 3 mRNA expression was upregulated and LMW H...