BACKGROUND Therapeutic drug monitoring (TDM) is essential practice when dosing drugs with a narrow therapeutic index in order to achieve a plasma drug concentration within a narrow target range above the efficacy concentration but below the toxicity concentration. However, TDM with dose individualisation is challenging during a double-blind clinical trial with laboratory staff and investigators...

The hyperconsciousness of radiation dose delivered to the patient during chest radiological X-ray procedures are prerequisite negate menace exposure. pinpoint this research is inquest doses received by for routine individual x-ray in health care system associated Kebbi State Government, Nigeria. Entrance Surface Dose and effective accordance with exposure factors collected real examinations wer...

UNLABELLED Handling and administration of radiopharmaceuticals are a key contributor to staff radiation dose. Shielded automated infusion devices potentially standardize and reduce radiation exposure during procedures. However, loading the devices adds incremental radiation exposure, which may mitigate dose savings. We measured radiation doses from the loading and use of an automated infusion d...

Aims This study sought to establish local adherence the following recommendations for management of short-term insomnia (under 3 months duration): 1. Sleep hygiene advice should be utilised prior pharmacological management. 2. A non-benzodiazepine hypnotic medication prescribed. 3. one-off trial dose benzodiazepine or Z-drug prescribed regular prescription.100% patients reviewed by medical staf...

High dose intravenous immunoglobulin therapy is becoming the established maintenance treatment for several neurological conditions. Therapeutic immunoglobulin is expensive and its administration is time consuming. Efficacy is variable and must be closely monitored. Here, we show that self infused immunoglobulin at home, combined with daily functional strength diaries to predict dose and dosage ...

PURPOSE A flat-panel detector based mobile isocentric C-arm for cone-beam CT (CBCT) has been developed to allow intraoperative 3D imaging with sub-millimeter spatial resolution and soft-tissue visibility. Image quality and radiation dose were evaluated in spinal surgery, commonly relying on lower-performance image intensifier based mobile C-arms. Scan protocols were developed for task-specific ...