OBJECTIVE To investigate a potential correlation between circulating cytokine and autoantibody levels and histopathological features in subgroups of patients with primary SS (pSS). METHODS Minor salivary gland biopsies from a cohort of 141 patients fulfilling the American-European consensus classification criteria for pSS were re-examined and grouped according to focus score (FS) and germinal...

Sirs, In the US/European Consensus Group (EUCG) classification criteria for Sjögren’s syndrome (SS) objective items, such as focal sialadenitis and serum presence of antiSS-A and anti-SS-B antibodies (anti-SS-A, anti-SS-B), are emphasized (1). In the sera of approximately 20% of SS patients no anti-SS-A or anti-SS-B can be detected at the time of diagnosis. However, in these ‘seronegative’ pati...

Annotation. The study of energy and adipokine metabolism indicators for the development course acute myocardial infarction (AMI) with comorbidity remains relevant. aim was to determine content in patients ST-segment elevation depending on presence absence type 2 diabetes mellitus (DM) after percutaneous coronary intervention (PCI). involved examination 60 AMI (Group 1) 74 2). Each group divided...

BACKGROUND Although European Borrelia burgdorferi sensu lato isolates have been divided into five genospecies, specific tools for the serotype characterization of only three genospecies are available. Monoclonals antibodies (mAbs) H3TS, D6 and I17.3 identify B. burgdorferi sensu stricto (ss.), B. garinii and B. afzelii respectively, but no mAbs are available to identify B. valaisiana. In the sa...

This study aimed to evaluate histologically the effect of irrigation with 400 ppm Sterilox, 2% and 5% sodium hypochlorite (NaOCl), with and without photo-activated therapy (PAD), in a single-visit root canal treatment of dog's teeth with apical periodontitis (AP). Ten dogs were randomly divided into two groups (n=5): with and without PAD, and the root canals into four subgroups, according to th...

The relationship between metallic cast crowns and tensile strength according to cement types submitted to thermocycling was studied. Seventy-two metallic crowns were cast with Verabond II Ni-Cr alloy and cemented in standardized preparations with 10 masculine tapering. Three types of finishing line (45-degree chamfered, 20-degree bevel shoulder and right shoulder) were made with diamond burs on...

Aims of the study were 1) to compare Hudgel's hyperbolic with Rohrer's polynomial model in describing the pressure-flow relationship, 2) to use this pressure-flow relationship to describe these resistances and to evaluate the effects of sleep stages on pharyngeal resistances, and 3) to compare these resistances to the pressure-to-flow ratio (DeltaP/V). We studied 12 patients: three with upper a...

PURPOSE To compare tear epidermal growth factor (EGF) concentration in dry eye (DE) conditions and determine correlations between EGF levels and severity of symptoms and ocular surface signs. METHODS In this prospective case-control study, 35 patients with DE, including subgroups with meibomian gland disease (MGD), Sjögren's syndrome (SS) aqueous tear deficiency, or neurotrophic keratopathy (...