نتایج جستجو برای: srb cytotoxic assay
تعداد نتایج: 272948 فیلتر نتایج به سال:
Sulfate reducing bacteria (SRB) have existed throughout much of Earth’s history and remain major contributors to carbon cycling in modern systems. Despite their importance, misconceptions about SRB are prevalent. In particular, SRB are commonly thought to lack oxygen tolerance and to exist only in anoxic environments. Through the last two decades, researchers have discovered that SRB can, in fa...
Under seasonally fluctuating redox conditions in sediment of Kiel Bay (eastern Baltic Sea), viable counts (MPN) of sulfate-reducing bacteria (SRB) ranged between 4 X 102 and 7 X 104 cm-3 These MPN appeared fairly independent of ambient redox potentials and followed peaks of phytoplankton productivity in the water column with a time lag of 2 to 3 wk. The relative proportions of SRB using acetate...
The bicyclo compounds possess a wide variety of activities so, in the present study we have develop a novel and simple method for the synthesis of such 3, 4-diphenyl-2, 5-diaza-bicyclo [4.3.1] decane derivatives. All the compounds synthesized were characterized by running TLC, IR, NMR and LCMS spectra. All the title compounds were screened for the determination of Cytotoxicity by MTT and SRB as...
Crude glycerol (CG) is an abundantly available and cheap by-product from biodiesel production. Value-added applications for CG are highly wanted by industry and several processes such as the use of CG for enhanced oil recovery have been proposed. The aim of this study was to evaluate the sulfide production of sulfate-reducing bacteria (SRB) indigenous to oil reservoirs using CG as substrate. Th...
Extracts from 27 marine algal species (14 Rhodophyta, 5 Phaeophyta, and 8 Chlorophyta) from the Yucatán Peninsula (Mexico) were evaluated for cytotoxic and antiproliferative activity by 3(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and sulforhodamine B (SRB) assays, respectively. To determine the specificity of cytotoxic activity against tumor cells, the selective index (SI...
Purpose: Many tumors exhibit defective cell-cycle checkpoint control and increased replicative stress. CHK1 is critically involved in the DNA damage response and maintenance of replication fork stability. We have therefore discovered a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor, CCT244747, and present its preclinical pharmacology and therapeutic activity. Exper...
BACKGROUND Knowledge about the prevalence of sexual risk behaviour (SRB) in adolescence is needed to prevent unwanted health consequences. Studies on SRB among adolescents in Central Europe are rare and mostly rely on a single indicator for SRB. This study aims to assess the association of behavioural and psychological factors with three types of SRB in adolescents in Central Europe. METHODS ...
isolation of some potent anti-tumor compounds from medicinal plants has motivated researchers to screen different parts of plant for their anti-tumor effects. it has been reported that several species of conifers posses’ cytotoxic activities on some tumor cell lines. here branchlets and berries of juniperus foetidissima and j. sabina were collected, dried and ethanol extracts of them obtained u...
OBJECTIVES Environmental and socio-demographic factors can influence the variation of the human sex ratio at birth (SRB = the ratio of males to males plus females). In particular, findings of seasonal, parental education, birth order, and maternal age effects on the SRB are not always in agreement, and a number of works report minimal variation. SETTING Here, we investigated the seasonality o...
Large-scale parallel scientific applications are generating huge amounts of data that tertiary storage systems emerge as a popular place to hold them. SRB, a uniform interface to various storage systems including tertiary storage systems such as HPSS, UniTree etc., becomes an important and convenient way to access tertiary data across networks in a distributed environment. But SRB is not optimi...
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