Three-hundred-seventy-eight, 18-21 day-old, pigs were used to evaluate subsequent weanling pig performance, during the second and third dietary phases, following initial phase 1 exposure to a commercial pelleted starter (CS) diet or farm processed wheat/barley/dried whey based starter diets prepared with, or without, spray dried porcine plasma (PPLS). One-half of the pigs in each treatment also...

In this work, oven-dried, freeze-dried and spray-dried agaro-oligosaccharide powders were characterized to investigate their physicochemical and antioxidant properties. Agarooligosaccharide powders were shown to exhibit high water solubility index (88.73 – 95.88%), water absorption capacity (0.96 – 2.57 g/g) and oil absorption capacity (0.40 – 0.45 g/g). Agarooligosaccharide powders were shown ...

The aim of this work was to study the effect of spray drying conditions on quality of coconut sugar powder and their characteristics. Effects of inlet air temperature (120°C, 150°C and 180°C) and maltodextrin concentrations (DE 9-12) at 10%, 20% and 30% (w/v) on physical properties of spray dried coconut sugar powder were investigated. Buchi mini spray dryer, model B-290, was used in this work....

Currently, the need for cooled storage and the impossibility of terminal sterilisation are major drawbacks in vaccine manufacturing and distribution. To overcome current restrictions a preclinical safety and efficacy study was conducted to evaluate new influenza A vaccine formulations regarding thermal resistance, resistance against irradiation-mediated damage and storage stability. We evaluate...

For particles to be useful medicinal aerosols, not only their aerodynamic diameter has to be on the order of a few micrometers but also they have to be chemically and physically stable. Manufacture of respirable particles is a technical challenge because as particles are reduced in size by conventional milling techniques, their cohesiveness greatly increases and physical and chemical stability ...

Aim of the present study was to investigate the impact of atomization and drying on the functionality of emulsions with an oil/water-interface (o/w-interface) consisting of beta-lactoglobulin (single layer emulsion) and sequentially adsorbed pectins with varying degree of methylation at pH<pI (bilayer emulsions). Thus, the emulsion systems were characterized with respect to their behavior durin...

Maintaining protein conformational stability and integrity during formulation is critical for developing protein pharmaceuticals. Accordingly, high sensitivity differential scanning calorimetry (HSDSC) and Fourier transform (FT)-Raman spectroscopy were employed to assess conformational stabilities (thermal stability and folding reversibility) and structural integrities, respectively, for three ...

Тhe aim of the study was identification and determination of the content of flavonoids in dry extracts of Teucrium polium, collected from Republic of Macedonia. Two different drying procedures were used, freeze and spray draying. In freeze-dried (FDE) and spray-dried (SDE) extracts of aerial parts of T. polium five flavone aglycones (luteolin, apigenin, cirsiliol, cirsimaritin and cirsilineol) ...

In prospect of developing an oral dosage form of Infliximab, for treatment of Crohn's disease and rheumatoid arthritis, freeze-drying (vial vs Lyoguard trays) and spray-drying were investigated as production method for stable powders. Dextran and inulin were used in combination with sucrose as stabilizing excipients. The drying processes did not affect Infliximab in these formulations, i.e. bot...