BACKGROUND Dosimetry in radionuclide therapy has the potential to allow for a treatment tailored to the individual patient. One therapeutic radiopharmaceutical where patient-specific dosimetry is feasible is 177Lu-DOTATATE, used for the treatment of neuroendocrine tumours. The emission of gamma photons by 177Lu allows for imaging with SPECT (single photon emission computed tomography). One impo...

Ischemic Heart Disease (IHD) poses an important diagnostic problem. Clinical picture of the disease is often atypical. SPECT is one of the main diagnostic tools in ischemic heart disease. Radioisotope study evaluates distribution of a radiopharmaceutical agent in the heart through a series of scintigraphic images taken by an external gamma camera. This article discusses the technical aspects of...

Total variation denoising filtering is proposed as an alternative to the Butterworth filter, which is widely used in the reconstruction of SPECT medical images. Its advantages lie in the preservation of the image edges while the noise is removed, as opposed to the blurring that characterizes Butterworth filtered images. However, results show that total variation filtering application to SPECT m...

OBJECTIVE A novel multifocal collimator, IQ-SPECT (Siemens) consists of SMARTZOOM, cardio-centric and 3D iterative SPECT reconstruction and makes it possible to perform MPI scans in a short time. The aims are to delineate the normal uptake in thallium-201 ((201)Tl) SPECT in each acquisition method and to compare the distribution between new and conventional protocol, especially in patients with...

Introduction: Acceptance test is a necessary procedure after SPECT system installation. The goal of this test is to reveal system's present condition, to compare it with manufacturer's specifications and also as a base for later tests. Methods: This study investigated four SPECT systems in Tehran. All of the quality control tests are performed on the basis of NEMA and IAEA recommendations...

Introduction:It is well-recognized that collimator-detector response (CDR) is the main image blurring factor in SPECT.  In this research, we compensated the images for CDR in molecular SPECT by using STIR reconstruction framework. Methods: To assess resolution recovery capability of the STIR, a phantom containing five point sources along with a micro Derenzo p...

We used single-photon emission computed tomography (SPECT) to determine the long-term risk of degenerative change after reconstruction of the anterior cruciate ligament (ACL). Our study population was a prospective series of 31 patients with a mean age at injury of 27.8 years (18 to 47) and a mean follow-up of ten years (9 to 13) after bone-patellar tendon-bone reconstruction of the ACL. The co...

| We deene ordered subset processing for standard algorithms (such as Expectation Maximization, EM) for image restoration from projections. Ordered subsets methods group projection data into an ordered sequence of subsets (or blocks). An iteration of ordered subsets EM is deened as a single pass through all the subsets, in each subset using the current estimate to initialise application of EM w...