UNLABELLED (123)I-Iomazenil brain SPECT has been used for the detection of epileptogenic foci, especially when surgical intervention is considered. Although epileptogenic foci exhibit a decrease in (123)I-iomazenil accumulation, normal cerebral cortices often exhibit similar findings because of thin cortical ribbons, gray matter atrophy, or pathologic brain structures. In the present study, we ...

OBJECTIVES A novel IQ-SPECT™ method has become widely used in clinical studies. The present study compares the quality of myocardial perfusion images (MPI) acquired using the IQ-SPECT™ (IQ-mode), conventional (180° apart: C-mode) and L-mode (90° apart: L-mode) systems. We assessed spatial resolution, image reproducibility and quantifiability using various physical phantoms. METHODS SPECT imag...

Objective: Reconstruction parameters must be optimized to approach the improved spatial resolution that is theoretically possible from modern SPECT imaging devices. One important reconstruction consideration is proper selection of the back-projection filter parameters. The aim of this study was to determine which Butterworth filter optimized image resolution for brain SPECT scans. Methods: Ten ...

Abstract We investigate the accuracy of direct attenuation correction (AC) in image domain for myocardial perfusion SPECT (single-photon emission computed tomography) imaging (MPI-SPECT) using residual (ResNet) and UNet deep convolutional neural networks. MPI-SPECT 99mTc-sestamibi images 99 patients were retrospectively included. ResNet networks trained non-attenuation-corrected as input, where...

Ischemic Heart Disease (IHD) poses an important diagnostic problem. Clinical picture of the disease is often atypical. SPECT is one of the main diagnostic tools in ischemic heart disease. Radioisotope study evaluates distribution of a radiopharmaceutical agent in the heart through a series of scintigraphic images taken by an external gamma camera. This article discusses the technical aspects of...

Total variation denoising filtering is proposed as an alternative to the Butterworth filter, which is widely used in the reconstruction of SPECT medical images. Its advantages lie in the preservation of the image edges while the noise is removed, as opposed to the blurring that characterizes Butterworth filtered images. However, results show that total variation filtering application to SPECT m...

introduction: in this study the evaluation of a platelet-based maximum penalized likelihood estimation (mple) for denoising spect images was performed and compared with other denoising methods such as wavelets or butterworth filtration. platelet-based mple factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to poisson n...

Background. The presence of a noise component on 3D images single-photon emission computed tomo­graphy (SPECT) brain significantly distorts the probability distribution function (PD) radioactive count rate in images. and further filtering data, based subjective assessment image quality, have significant impact calculation volumetric cerebral blood flow values uptake asymmetry radiopharmaceutica...

Using nuclear medicine techniques, physiologic activity and processes can be identified in a way that is unique from other modalities. Oftentimes it is helpful to know the exact location of the physiologic uptake that is visualized on a scan. Knowing the exact location can sometimes help to distinguish normal from abnormal physiologic uptake. When an abnormality has been identified, knowing the...

Image registration is the process of transforming different image data sets of an object into the same coordinate system. This is a relevant task in the field of medical imaging; one of its objectives is to combine information from different imaging modalities. The main goal of this study is the registration of renal SPECT (Single Photon Emission Computerized Tomography) images and a sparse set...