Significant ptosis is a relative contraindication for nipple-sparing mastectomy and reconstruction. Repositioning of the nipple on the reconstructed breast is best accomplished using a pedicled approach that is risky in the immediate setting. We utilized a surgical delay before reconstruction that allowed for repositioning of the nipple-areola complex on an inferior pedicle. This also allows fo...

OBJECTIVES To prospectively study whether urinary function and bother are directly related to neurovascular bundle preservation at radical prostatectomy using validated quality-of-life questionnaires. METHODS A total of 91 consecutive patients undergoing radical prostatectomy were prospectively studied using the University of California, Los Angeles, Prostate Cancer Index and the Internationa...

The treatment of aortic root and ascending aortic aneurysms often requires addressing concomitant aortic valve pathology. In the setting of aortic stenosis secondary to cusp degeneration, aortic valve replacement (AVR) is performed. However, when patients present with aortic insufficiency and normal cusp anatomy, a dilemma arises. Historically valve replacement has been performed; however, curr...

OBJECTIVE Evaluate the results of various surgical procedures used for aortic root replacement in children with aortic root aneurysm. METHODS Between 1986 and 2007, 23 children (less than 16 years of age, mean age: 8.1+/-5.1 years) underwent elective aortic root replacement for aortic root aneurysm (with associated aortic insufficiency in 10 patients). All had connective tissue defect syndrom...

Purpose To identify predictors of best corrected visual acuity (BCVA) in eyes with foveal-sparing geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Methods Best corrected visual acuity (Early Treatment Diabetic Retinopathy Study charts); serial fundus autofluorescence; and near-infrared reflectance images of patients participating in the FAM (NCT00393692) and DSGA (...

PURPOSE To provide a clinical and genetic description of a patient cohort with Stargardt disease (STGD1) with identifiable foveal sparing. METHODS Patients with retinal atrophy (defined as an absence of autofluorescence) that surrounded the fovea by at least 180° and did not include the fovea were defined as having foveal sparing; eyes with visual acuity (VA) worse than 20/200 were excluded. ...

Retinitis pigmentosa (RP) is an inherited retinal disease caused by the degeneration of photoreceptors and retinal pigment epithelium cells within the eye. The present study aimed to evaluate the effectiveness of multicolor imaging as a novel technique for the depiction of morphological features in the macular area of patients with RP. Additionally, the correlation between the size of the macul...

A standard approach in the surgical treatment of severe aortic regurgitation and/or aortic root dilatation is Bentall procedure, it means replacement of the aortic valve and ascending aorta with a composite graft including mechanical or biological valve. The original technique described by Bentall and De Bono in 1968 (5). This is a „safe“ method with low mortality, but patients have to accept t...