To the Editor: Recently, Li et al. reported on the frequency of the derived allele ADH1B*47His in Eastern and Western Asia. The data were based on meta-analysis of the published results for 131 populations and the results of genotyping of samples from 37 additional populations, performed by the authors. The authors made the suggestion that there had been separate and independent increases in th...

The rubber boom across much of Southeast Asia has led to environmental destruction, and the resultant crash in the price of rubber has destabilised livelihoods. We investigated the necessary factors required to enable a transition towards a more sustainable model for rubber cultivation in Southwest China (i.e. the 'greening' of rubber cultivation), using a framework for the integrative study of...

Subsistence intensification – the extraction of increased amounts of energy from a given area at the expense of foraging efficiency – figures prominently in discussions of the Epipaleolithic period (ca. 21,000–11,500 cal bp). Despite their paramount status, intensification trends are not often subjected to rigorous testing using multiple archaeological data sets. This study aims to fill this ga...

[1] A global 3-D chemical transport model is used to analyze observations of carbon monoxide (CO) and upper tropospheric clouds from the EOS Microwave Limb Sounder (MLS). MLS observations during 25 August–6 September 2004 reveal elevated CO and dense high clouds in the upper troposphere over the Tibetan plateau and southwest China, collocating with the upper level Tibetan anticyclone. Model sim...

Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina. The two hypotheses about the origin of VL in the NW suggest (1) recent importation of L. infantum from the Old World (OW), or (2) an indigenous origin and a distinct taxonomic rank for the NW parasite. Multilocu...

Global climate underwent a major reorganization when the Antarctic ice sheet expanded ~14 million years ago (Ma) (1). This event affected global atmospheric circulation, including the strength and position of the westerlies and the Intertropical Convergence Zone (ITCZ), and, therefore, precipitation patterns (2-5). We present new shallow-marine sediment records from the continental shelf of Aus...

The number of Late Pleistocene hominin species and the timing of their extinction are issues receiving renewed attention following genomic evidence for interbreeding between the ancestors of some living humans and archaic taxa. Yet, major gaps in the fossil record and uncertainties surrounding the age of key fossils have meant that these questions remain poorly understood. Here we describe and ...

The Department of Defense launched a mandatory anthrax immunization program for military personnel in December 1997. This program has been criticized for many reasons, including concern over side effects. This study was designed to give a quick answer to the question of whether vaccinated persons who deployed to southwest Asia were more likely to seek medical care upon their return than their u...

This article looks at three types of mental maps projected on Southwest Asia during the twentieth century and examines how they were assimilated, reframed or refused by political actors in the region itself. (1) The concept of the ‘Fertile Crescent’ was connected to the archaeological exploration of ancient memorial landscapes that testified to the region’s ancient superiority and, hence, could...