We thank Dr Mubareka and Dr Rubinstein for their thoughtful commentary [1] related to our recent publication on aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis [2]. We would like to provide some additional clarifications related to the formulation of colistin used in our study because the commen...

The Ethics Task Force of the EAPC has done a significant job in forwarding the discussion of the relationship between palliative care and euthanasia, as the wealth of international commentary on the document surely illustrates. The position paper is commendably succinct and, in some respects, unambiguous in the views defended. Notably, the document abjures discussion of anything other than volu...

One of the themes of Emotion and Decision-Making Explained (Rolls, 2014c) is that there are multiple routes to emotionrelated responses, with some illustrated in Fig. 1. Brain systems involved in decoding stimuli in terms of whether they are instrumental reinforcers so that goal directed actions may be performed to obtain or avoid the stimuli are emphasized as being important for emotional stat...

The paper presents a software agents society, which implements a more efficient control and monitoring system for a complex heterogeneous system – multiple hydroelectric power plants connected in a chain on Somes River. The agent society can be superimposed over the existing SCADA control and monitoring network and aims to increase performance, efficiency and stability in the existing monitorin...

By means of a Q-banding technique, virtually every chromosome in two heteroploid mouse cell lines, RAG and MSWBS, has been identified. The origin of 60 to 80% of the chromosomes has been established; the remaining chromo somes can be identified as markers characteristic of the cell line. The extent of chromosome heterogeneity has been ex amined and compared in these two mouse tumor cell lines. ...

1. It is my first and pleasant duty to thank all commentators for their attentive and insightful contributions. I learned a lot following their arguments and numerous instructive references. No doubt many of the topics addressed by the commentators are fundamental and would deserve a full article of their own. Here, I can just focus on the main criticisms and sketch future lines of research for...

The commentators raised many interesting ideas in response to Armstrong and Pagell (2003), from which one general theme emerges: The commentators claim that management science lacks the incentives to encourage efforts to develop and communicate grounded principles. As a result, academics often conduct their research as an intellectual exercise with little concern as to whether their findings mi...

The commentators raised issues relevant to all three important theses of The Origin of Concepts (TOOC). Some questioned the very existence of innate representational primitives, and others questioned my claims about their richness and whether they should be thought of as concepts. Some questioned the existence of conceptual discontinuity in the course of knowledge acquisition and others argued ...