BACKGROUND In 2011 the C9ORF72 repeat expansion was identified as the most frequent genetic mutation underlying FTD and ALS. The main aim of this study was to investigate clinical characteristics in a large C9ORF72-positive FTD family, and to compare these with the neuropathological findings. METHODS The clinical records of 12 related FTD patients were thoroughly evaluated. The five neuropath...

The objective of the study was to develop and evaluate a 2-day burnout intervention program focused at enhancing coping with stresses observed in teachers' work. Karasek's job stress model was used as the theoretical framework. The aim of the intervention was to teach participants to deal better with high job demands and low job control. Some cognitive-behavioural methods of overcoming workload...

For patients with borderline personality disorder, separations from significant figures in their lives, including therapists, are thought to be particularly painful. According to clinical wisdom, these patients manifest aggressive and self-destructive behavior around the time of separation. However, virtually no empirical studies have been conducted to test these beliefs. In this study, the beh...

OBJECTIVE The Child Behavior Checklist (CBCL; T. M. Achenbach, 1991), when used to assess the behavior of children with diabetes, may contain confounds because some behavioral items can have a physiologic etiology, and may skew reports of behavioral disturbance. METHODS Two techniques were used to disentangle possible scoring confounds in the behavioral ratings of children with and without di...