نتایج جستجو برای: somatic chromosome

تعداد نتایج: 159086  

2010
Nancy P. Thorogood Carolyn J. Brown

BACKGROUND X-chromosome inactivation occurs early in mammalian development and results in the inactive X chromosome acquiring numerous hallmarks of heterochromatin. While XIST is a key player in the inactivation process, the method of action of this ncRNA is yet to be determined. METHODOLOGY/PRINCIPAL FINDINGS To assess which features of heterochromatin may be directly recruited by the expres...

Journal: :Nucleic acids research 1990
R G Lafreniere H F Willard

Source/Description: cpX12 is a 1.1 kb EcoRI single-copy genomic fragment cloned into pAT153 from a pool of 100 cosmids isolated from a human/hamster somatic cell hybrid containing only the human X chromosome (1). Polymorphism: cpX12 reveals a two-allele restriction fragment length polymorphism with bands at 0.7 kb and 1.9 kb (Al) or 2.6 kb (A2) after Southern blot analysis of human genomic DNA ...

Journal: :Biologia 2021

The comparative chromosomal features of four species belonging to family Apocynaceae from Northeastern Thailand were studied the root tips. somatic chromosome numbers all specimens found be 2n = 36 for Allamanda blanchetii, 18 A. cathartica, 20 in schottii and 52 Cryptostegia grandiflora. cathartica have same number previous except C. grandiflora differs previously reported. Moreover, has never...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1963
M M Grumbach A Morishima J H Taylor

Striking differences are demonstrable in the morphological and functional state of the two X-chromosomes in somatic cells of the female of a variety of mammalian species. Recent studies'-10 have led to the concept that in somatic cells one of the two X-chromosomes, which may be of either maternal or paternal origin, undergoes a change of state which first becomes manifest during early ontogeny....

Journal: :Current Biology 2001
Masako Tada Yousuke Takahama Kuniya Abe Norio Nakatsuji Takashi Tada

The resetting of a somatic epigenotype to a totipotential state has been demonstrated by successful animal cloning, via transplantation of somatic nuclei into enucleated oocytes. We have established an experimental system, which reproduces the nuclear reprogramming of somatic cells in vitro by fusing adult thymocytes with embryonic stem (ES) cells. Analysis of the lymphoid-cell-specific V-(D)-J...

2017
Madeleine Arseneault Jean Monlong Naveen S. Vasudev Ruhina S. Laskar Maryam Safisamghabadi Patricia Harnden Lars Egevad Nazanin Nourbehesht Pudchalaluck Panichnantakul Ivana Holcatova Antonin Brisuda Vladimir Janout Helena Kollarova Lenka Foretova Marie Navratilova Dana Mates Viorel Jinga David Zaridze Anush Mukeria Pouria Jandaghi Paul Brennan Alvis Brazma Jorg Tost Ghislaine Scelo Rosamonde E. Banks Mark Lathrop Guillaume Bourque Yasser Riazalhosseini

Recent genomic studies of sporadic clear cell renal cell carcinoma (ccRCC) have uncovered novel driver genes and pathways. Given the unequal incidence rates among men and women (male:female incidence ratio approaches 2:1), we compared the genome-wide distribution of the chromosomal abnormalities in both sexes. We observed a higher frequency for the somatic recurrent chromosomal copy number vari...

Journal: :Cytologia 2021

Medicinally important five Phyllanthus species viz. P. acidus (L.) Skeels, emblica L. (small fruit form), (large niruri L., reticulatus Poir. and urinaria were cytogenetically studied through orcein-staining for authentic characterization. This genus showed variation in somatic chromosome numbers such as 2n=2x=26 (x=13) acidus, reticulatus, 2n=6x=48 (x=8) 2n=10x=100 (x=10) (both small large for...

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