Opioids are some of the most effective pain-relieving drugs used in the clinical management of pain (Gilman et al. 1990). In addition to their analgesic effect, opioid peptides and alkaloids also affect a number of physiological functions including hormone secretion, neurotransmitter release, feeding, gastrointestinal motility, and respiratory activity (Pasternak 1988). Extensive physiological,...

We show that AC0 circuits on n variables with depth d and sizem have at most 2−Ω(k/ logd−1 m) of their Fourier mass at level k or above. Our proof builds on a previous result by Håstad (SICOMP, 2014) who proved this bound for the special case k = n. Our result improves the seminal result of Linial, Mansour and Nisan (JACM, 1993) and is tight up to the constants hidden in the Ω notation. As an a...

Known-key distinguishers for block ciphers were proposed by Knudsen and Rijmen at ASIACRYPT 2007 and have been a major research topic in cryptanalysis since then. A formalization of known-key attacks in general is known to be difficult. In this paper, we tackle this problem for the case of block ciphers based on ideal components such as random permutations and random functions as well as propos...

Radio networks (RN) are distributed systems (ad hoc networks) consisting in n 2 radio stations. Assum8 ing the number n unknown, two distinct models of RN without collision detection (no-CD) are addressed: 9 the model with weak no-CD RN and the one with strong no-CD RN. We design and analyze two distributed 10 leader election protocols, each one running in each of the above two (no-CD RN) model...

The iterated Even–Mansour (EM) ciphers form the basis of many blockcipher designs. Several results have established their security in the CPA/CCA models, under related-key attacks, and in the indifferentiability framework. In this work, we study the Even–Mansour ciphers under key-dependent message (KDM) attacks. KDM security is particularly relevant for blockciphers since non-expanding mechanis...

We study a novel mechanism design model in which agents arrive sequentially and each in turn chooses one action from a set of actions with unknown rewards. The information that becomes available affects the incentives of an agent to explore and generate new information. We characterize the optimal disclosure policy of a planner whose goal is to maximizes social welfare. One interpretation for o...

We read with interest the article by Mansour et al. (1) published entitled "Echocardiographic predictors of atrial fibrillation after mitral valve replacement." in Anatol J Cardiol 2017;17:3346. As expected, postoperative atrial fibrillation (POAF) is more likely to occur in patients with mitral valve disease when the preoperative left atrial diameter increases. However, there is a particular a...