Abstract Renal cell carcinoma, notably clear renal carcinoma in particular, show remarkable predisposition for intravenous growth. Retrograde venous invasion results intravascular emboli sinus and intrarenal veins, nodules parenchyma (after extravascular spread). In our experience, we observed this phenomenon five cases out of 204 tumors: four carcinomas (4/166 or 2.4%) 12.5% those with major v...

Renal cell carcinoma accounts for 85% of all solid renal tumors in adults. Nearly one quarter of patients has distant metastasis at presentation while another 50% develop metastasis during follow-up. A small percentage of these are solitary metastasis. We report here a case of solitary bone sternal metastasis as an initial presentation of clear-cell renal cell carcinoma in a 56-year-old woman. ...

Renal cell carcinoma (RCC) usually metastasizes to lung, liver, bone and brain. We report a case of an elderly man who underwent radical nephrectomy for renal developed metastasis in the plane between contralateral psoas muscle quadratus lumborum 11 years after operation J Enam Med Col 2021; 11(1): 52-54

Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...

We report a rare clinical presentation of renal cell carcinoma in the form of small bowel obstruction which was secondary to a metastatic ileal intussusception. Intussusception in the elderly is most commonly due to an underlying neoplasm, however metastases from a renal cell carcinoma is very uncommon. We present clinical details, radiological and pathological findings of the case followed by ...

Oncocytoma and chromophobe renal cell carcinoma may show a certain degree of histological overlap. The problem of differentiating both types is expected to increase because of the more frequent use of needle biopsies to diagnose small renal masses. In this study. The expression and the possible diagnostic utility of S 100 was evaluated in both oncocytoma and chromophobe renal cell carcinoma, us...

Renal metastasis from non-small cell lung cancer is rather uncommon. The mechanism underlying the occurrence of metastasis in this site is still not well understood. We report a case of a 53-year-old Chinese woman who had moderately differentiated squamous cell carcinoma of the lung. After a ten months post-surgery interval of disease free survival, computed tomography (CT) scan found that left...

Sarcomatoid transformation, wherein an epithelioid carcinomatous tumour component coexists with a sarcomatoid histology, is a predictor of poor prognosis in clear cell renal cell carcinoma. Our understanding of sarcomatoid change has been hindered by the lack of molecular examination. Thus, we sought to characterize molecularly the biphasic epithelioid and sarcomatoid components of sarcomatoid ...

Renal cell carcinoma is a common neoplasia of the adult kidney that accounts for about 3% of adult malignancies. Clear cell renal carcinoma is the most frequent subtype of kidney cancer and 20-40% of patients develop metastases. The absence of appropriate biomarkers complicates diagnosis and prognosis of this disease. In this regard, small noncoding RNAs (microRNAs), which are mutated in severa...

Chromophobe renal cell carcinoma (CHRC) is a neoplasm of the kidney with clinicopathologic peculiarities that seems to be of better prognosis than conventional renal cell carcinoma. Classical and eosinophilic types are the two histological variants recorded. Also, it has been described in association with carcinoma of collecting ducts, conventional renal cell carcinoma and sarcomatoid renal cel...