BACKGROUND There are many scanners of glass slides on the market now. Quality of digital images produced by them may be different and pathologists who examine virtual slides on a monitor may subjectively evaluate it. However, objective comparison of quality of digital slides captured by various devices requires assessment algorithms, which will be automatically executed. METHODS In this work ...

Glass microscope slides are considered by many as the substrate of choice for microarray manufacturing due to their amenability to various surface chemistry modifications. The use of silanes to attach various functional groups onto glass slides has provided a versatile tool for the covalent immobilization of many diverse biomolecules of interest. We recently noted a dramatic reduction in biomol...

According to the frequentists theory, it is assumed that unknown parameter θ is some xed number or vector. Given parameter value θ, we observe sample data X from distribution f(·|θ). To estimate parameter θ, we introduce an estimator T (X) which is a statistic, i.e. function of the data. This statistic is a random variable, since X. That is, the randomness here comes from randomness of sampling...

Light-emitting diode fluorescence microscopy is being scaled up for tuberculosis control, but fading of auramine-stained slides could compromise external quality assurance. We stored auramine-stained slides and reexamined them over time. Slides stored in all environments faded quickly, with significant changes in the proportion of positive slides in as little as 1 week.

The reproducibility of a test result is a critical component of its clinical utility. Little information is available concerning the intrarater reproducibility of cytologic assessments. This study evaluated the reproducibility of cytologic interpretation of epithelial cells obtained from ductal lavage (DL), a minimally invasive method used to obtain sample cells from breast tissue. Two cytospin...

A new robust method to embed imperceptibly a watermark image into the slides of a presentation is proposed. The watermark is partitioned into blocks and embedded into the space characters existing in the slides in a repeating pseudo-random sequence. The embedding is achieved by changing the colors of the space characters into new ones which are results of encoding the contents and indices of th...

The reproducibility of a test result is a critical component of its clinical utility. Little information is available concerning the intrarater reproducibility of cytologic assessments. This study evaluated the reproducibility of cytologic interpretation of epithelial cells obtained from ductal lavage (DL), a minimally invasive method used to obtain sample cells from breast tissue. Two cytospin...

OBJECTIVE To assess interrater reliability in the diagnosis of malignant melanoma in children. DESIGN, SETTING, AND PARTICIPANTS We collected 85 slides of melanomas diagnosed in patients younger than 17 years through a network of dermatopathologists and dermatologists. The slides were classified into 3 categories: (1) slides from children with metastatic melanoma; (2) slides from disease-free...

Engineering educators often create slides for classroom presentations to instruct students. In turn, engineering students often create slides for classroompresentations to demonstratewhat they have learned.Given howoften presentation slides are projected and viewed by engineering educators and students, those slides should follow principles of multimedia learning to foster high audience compreh...