BACKGROUND The presence of interictal epileptiform discharges (IEDs) in electroencephalogram (EEG) is diagnostic of epilepsy. Latent IEDs are activated during sleep. Anti-epileptic drugs (AEDs) improve sleep. AEDs, sleep, and IEDs may interact and affect epilepsy management. PURPOSE To explore the occurrence of IEDs and its association with sleep and AED status in suspected patients of epilep...

In the present study, the alteration in the sleep EEG in rats due to chronic exposure to low-level non-thermal electromagnetic radiation was investigated. Two types of radiation fields were used; 900 MHz unmodulated wave and 900 MHz modulated at 8 and 16 Hz waves. Animals has exposed to radiation fields for 1 month (1 h/day). EEG power spectral analyses of exposed and control animals during slo...

The electroencephalogram (EEG) is a complex signal and an important brain state indicator (e.g. waking, sleep, seizure). Modern brain research is intimately linked to the feasibility to record the EEG and to its quantitative analysis. EEG spectral analysis (decomposing a signal into its constituent frequency components) is an important method to investigate brain activity. Basic principals of s...

OBJECTIVE We investigate the relationship between changes in heart rate variability and electroencephalographic (EEG) activity during sleep. METHOD Nine male subjects with regular non-rapid-eye movement-rapid-eye movement (NREM-REM) sleep cycles were included in the study. They underwent EEG and cardiac recordings during one experimental night. Heart rate variability was determined over 5-min...

The impact of a 40 h sleep deprivation versus a 40 h multiple nap paradigm on topographic and temporal aspects of electroencephalographic (EEG) activity during the subsequent recovery sleep was investigated in 10 young volunteers in a controlled 'constant posture' protocol. The accumulation of sleep pressure with extended wakefulness could be significantly attenuated by intermittent naps. The d...

The basal forebrain (BF) is known for its role in cortical and behavioral activation, and has been postulated to have a role in compensatory mechanisms after sleep loss. However, specific neuronal phenotypes responsible for these roles are unclear. We investigated the effects of ibotenate (IBO) and 192IgG-saporin (SAP) lesions of the caudal BF on spontaneous sleep-waking and electroencephalogra...

OF THESIS AGING AND SLEEP STAGE EFFECTS ON ENTROPY OF ELECTROENCEPHALOGRAM SIGNALS The aging brain is characterized by alteration in synaptic contacts, which leads to decline of motor and cognitive functions. These changes are reflected in the age related shifts in power spectrum of electroencephalogram (EEG) signals in both wakefulness and sleep. Various non-linear measures have been used to o...

OBJECTIVE To characterise and quantify the EEG during sleep in healthy newborns in the early newborn period. METHODS Continuous multi-channel video-EEG data was recorded for up to 2 hours in normal newborns within 12 hours of birth. The total amount of active (AS) and quiet sleep (QS) was calculated in the first hour of recording. The EEG signal was quantitatively analysed for symmetry and sy...

Detection and quantification of sleep arousals is an important issue, as the frequent arousals are known to reduce the quality of sleep and cause daytime sleepiness. In typical sleep staging, electroencephalograph (EEG) is the core signal and based on the visual inspection of the frequency content of EEG, non-rapid eye movement sleep is staged into four somewhat rough categories. In this study,...

A major limitation in the study of sleep breathing disorders in mouse models of pathology is the need to combine whole-body plethysmography (WBP) to measure respiration with electroencephalography/electromyography (EEG/EMG) to discriminate wake-sleep states. However, murine wake-sleep states may be discriminated from breathing and body movements registered by the WBP signal alone. Our goal was ...