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Intermittent hypoxia, a powerful and unique stimulus, leads to physiologic changes that are distinct from those associated with either single or continuous hypoxic exposure. There is an accumulating body of evidence that the neurocognitive, inflammatory and cardiovascular symptoms that characterize the syndrome of obstructive sleep apnea are linked to the stimulus of intermittent hypoxia. In ad...

_______________________________________________________________________________________________________ 1. MD. Associate Professor of Otolaryngology, Department & Research Center of Otolaryngology , Head and Neck Surgery, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences. [email protected] 2. (Corresponding author) MD. General Physician, Department & Research Center of Otolar...

OBJECTIVE Although obstructive sleep apnea (OSA) is not a life-threatening disease, very few studies have compared differences in healthcare service utilization between patients with and those without OSA in an Asian population according to different age groups. This study attempted to investigate differences in healthcare service utilization between patients with and those without OSA in diffe...

Obstructive sleep apnea is a common disorder in which the airway repetitively collapses during sleep; patients with sleep apnea are often inattentive and sleepy. This review discusses driving performance and automobile accidents in patients with sleep apnea. Finally, we discuss the effect of therapy upon driving performance and reported accidents in these subjects.

BACKGROUND Obstructive sleep apnea syndrome (OSAS) is a very important and prevalent disease, which is associated with a poor quality of life in many patients. Treatments for OSAS include surgery, Continuous Positive Air way Pressure, and an intraoral mandibular repositioner (IOMR), but the tendency of sleep centers is to emphasize the apnea index, neglecting quality of life as treatment outcom...

We evaluated naturalistic driving in 65 drivers with obstructive sleep apnea (OSA) before and after positive airway pressure (PAP) therapy and in 43 comparison drivers. Driving performance metrics included speed (mean, variability), and lateral, and longitudinal acceleration (g's). Driver state measures included sleepiness and attention to the driving task based on sampled trigger and baseline ...

This is an overview for the non-specialist of the pathophysiology, workup and treatment of the obstructive sleep apnea syndrome. The mechanisms leading to upper airway closure during sleep are discussed, as well as the current theoretical and experimental concepts for the apnea-induced arousal response and the consequent changes in sleep architecture and quality. Epidemiological data are summar...

CONCLUSION The new mattress and pillow for prone positioning (MPP) is efficient in reducing the apnoea-hypopnoea index (AHI) and oxygen desaturation index (ODI) in most patients with obstructive sleep apnoea (OSA), with satisfactory compliance. OBJECTIVE The aim of the present study was to evaluate the effect of the prone body and head sleep position on severity of disease in patients with OS...