An uncommon skin manifestation of Dermatitis Herpetiformis is palmar and plantar purpura. Dermoscopic examination is useful for any skin condition since it allows recognition of structures that are not discernible to the naked eye. A 22 year-old Caucasian man was admitted with excoriated lesions and pruritus. Petechial lesions could be seen on volar aspect of the digits on the hands and feet. D...

Zinc deficiency can be an autosomal recessive inherited or acquired disorder and is classically characterized by acral and periorificial dermatitis, alopecia, and diarrhea. We report a case of acquired zinc deficiency in a premature 6-week-old boy with typical skin manifestation of zinc deficiency and decreased plasma zinc level. After starting zinc replacement therapy, the skin lesions complet...

strongyloides stercoralis is a free living tropical and semitropical soil nematode which its larva penetrates skin. it can complete its life cycle in human body and causes autoinfection. most patients have no frank symptoms. but respiratory, gastrointestinal and skin manifestation may occur. we report a 76 year old man admitted to emergency room with muscle weakness, dyspnea, nausea, vomiting w...

Background: Dermatophyte is a group of keratinophilic fungi that cause various skin lesions depending on the affected area. Dermatophytosis is usually diagnosed by clinical manifestation and confirmed by direct microscopy or fungal culture. There might be diagnostic difficulty with the presence of atypical dermatophytosis. Atypical dermatophytosis presents with clinical appearances ranging from...

BACKGROUND Hepatosplenic T-cell lymphoma is a rare malignancy in childhood. CASE CHARACTERISTICS A 12-year-old boy who presented a pyrexia of unknown origin, multiple skin and lesions and marked hepatosplenomegaly. OBSERVATION Bone marrow aspirate cytology showed no blast cells. Splenectomy was done, and spleen showed infiltration with atypical lymphoid cells positive for CD3, CD8 and T-cel...

In 2-8% of patients with melanoma, the first clinical manifestation of the disease may be skin metastasis. In these cases, differential diagnosis with the primary melanoma, benign melanocytic lesions, and other malignant and benign skin growths is particularly challenging. For this reason, the dermatologist's approach to cutaneous metastases of malignant melanoma calls for knowledge of the grea...

On rare occasions, skin lesions are the first local of metastatic manifestation of internal malignancies. In case of no previous diagnosis of these tumors, the approach of suspicious skin lesions becomes a challenge, especially in differentiating cutaneous metastases and adnexal primary neoplasms. Currently, besides epidemiologic, dermoscopic and histopathologic aspects, the evaluation also int...

The causative agent of leprosy is Mycobacterium leprae (M. leprae), which establishes infectious lesions in the skin. Leprosy is classified based on the clinical manifestation, the host’s immune response and skin symptoms. M. leprae is an intracellular pathogen that invades keratinocytes, macrophages, dendritic cells and Schwann cells and replicates within these cells. M. leprae-infected kerati...

Although, erythema nodosum is a common skin manifestation associated with syphilis, nodular vasculitis is a rare feature. Here, we describe a case of a 22-year-old, human immunedeficiency virus negative, non-immunocompromised man who developed recurrent oral and scrotal ulcers with nodular lesions of the lower extremitie. Behçet's disease was initially suspected, however, his serologic test for...