OBJECTIVE To determine whether or not patient race and ethnicity affect sinonasal cancer survival. STUDY DESIGN Retrospective database analysis. SETTING National Cancer Institute's Surveillance, Epidemiology, and End Results Database, 1988-2010. SUBJECTS AND METHODS Sinonasal carcinoma cases were extracted according to site codes and histology recode-broad groupings. The cohort was used t...

BACKGROUND Sinonasal undifferentiated carcinoma (SNUC) is a rare, aggressive malignancy of unknown etiology with a poor overall prognosis. Its relative rarity has made it difficult to determine the impact of different treatment modalities on survival. METHODS Retrospective study of cases in the National Cancer Data Base (NCDB). NCDB cases that were diagnosed as having SNUC between January 1, ...

Sarcoma is an uncommon histopathological presentation of sinonasal tumors, comprising ~15% of all cases; liposarcoma is particularly uncommon. An analysis of the available medical literature revealed no prior reports of dedifferentiated liposarcoma (DDLPS) of the sinonasal cavity. This case report presents a rare case of DDLPS of the sinonasal cavity. A 40-year old six-week pregnant female was ...

BACKGROUND Our objective was to identify the expression of epidermal growth factor receptor (EGFR), c-KIT (CD117), and HER2/neu in sinonasal undifferentiated carcinoma (SNUC). METHODS Immunohistochemistry for c-KIT (CD117), EGFR, and HER2/neu was performed on paraffin-embedded tissue from SNUC cases. A search for activating mutations in c-kit exons 9, 11, 13, and 17 or gene amplification was ...