نتایج جستجو برای: siderophores
تعداد نتایج: 2066 فیلتر نتایج به سال:
Many bacteria rely on siderophores to extract iron from the environment. However, acquisition of iron-loaded siderophores is dependent on high-affinity uptake systems that are not produced under high-iron conditions. The fact that bacteria are able to maintain iron homeostasis in the absence of siderophores indicates that alternative iron acquisition systems exist. It has been speculated that s...
The surge of interest in fluorescent pseudomonads was spurred by discoveries that members of this group are capable of increasing plant growth and suppressing disease upon introduction into the soil or rhizosphere (Burr et al., 1978; Kloepper and Schroth, 1981; Olsen and Misaghi, 1982, 1984; Weller and Cook, 1983). These bacteria produce iron chelators (siderophores) in vitro with high stabilit...
Neisseria gonorrhoeae produces no known siderophores but can employ host-derived, iron-binding proteins, including transferrin and lactoferrin, as iron sources. Given the propensity of this pathogen to hijack rather than synthesize iron-sequestering molecules, we hypothesized that the ability to use siderophores produced by other bacteria, or xenosiderophores, may also play a role in the surviv...
In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes.
The iroA locus encodes five genes (iroB, iroC, iroD, iroE, iroN) that are found in pathogenic Salmonella and Escherichia coli strains. We recently reported that IroB is an enterobactin (Ent) C-glucosyltransferase, converting the siderophore into mono-, di-, and triglucosyl enterobactins (MGE, DGE, and TGE, respectively). Here, we report the characterization of IroD and IroE as esterases for the...
In Escherichia coli, the biosynthetic pathways of several small iron-scavenging molecules known as siderophores (enterobactin, salmochelins and yersiniabactin) and of a genotoxin (colibactin) are known to require a 4'-phosphopantetheinyl transferase (PPTase). Only two PPTases have been clearly identified: EntD and ClbA. The gene coding for EntD is part of the core genome of E. coli, whereas Clb...
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