The dynamical reaction of the particles accelerated at a shock front by the first order Fermi process can be determined within kinetic models that account for both the hydrodynamics of the shocked fluid and the transport of the accelerated particles. These models predict the appearance of multiple solutions, all physically allowed. We discuss here the role of injection in selecting the real sol...

The current study investigates the impact of real oil price shocks on Eurozone banking sector from February 2009 to 2022, using Structural Vector Autoregressive method distinguish reaction between bank indices and three structural indicators in market shocks. include global demand, supply shock, specific Our findings show that responds positively toward an oil-specific demand shock (oil price) ...

Synthesis of mRNA in trypanosomes involves an apparent trans-splicing reaction whereby a common 39-nucleotide mini-exon sequence is joined to the protein-coding exon of a mRNA precursor. We have previously shown (Muhich, M. L., and Boothroyd, J. C. (1988) Mol. Cell. Biol. 8, 3837-3846) that the trans-splicing pathway of Trypanosoma brucei is sensitive to disruption by severe heat shock. Here we...

In the United States, >750,000 patients annually are thought to be at high risk for developing septic shock, with mortality rates reaching 60%. Thus, huge societal and financial costs are associated with this syndrome. Because of the high incidence and poor prognosis of septic shock, basic research has focused on the innate immune system for >2 decades. The pathophysiology of severe sepsis/shoc...

Detonation of a three-dimensional reactive nonisotropic molecular crystal is modeled using molecular dynamics simulations. The detonation process is initiated by an impulse, followed by the creation of a stable fast reactive shock wave. The terminal shock velocity is independent of the initiation conditions. Further analysis shows supersonic propagation decoupled from the dynamics of the decomp...

Drug intoxication with disulfiram is a rare condition that may lead to severe and potentially fatal cardiovascular manifestations such as cardiogenic shock. We report the case of a female patient with refractory shock after deliberate self-poisoning with disulfiram. Clinical, biochemical and echocardiographic assessment, as well as invasive monitoring confirmed cardiogenic shock associated with...

Abstract Previous studies (Watt et al. in J Eng Math 75(1):1, 2012; Cartwright and Falle 115(1):157, 2019) have shown that a streamline based approach to modelling of steady state detonations can produce good results for rate laws which maximal reaction at the shock. In this paper we consider Variational Streamline Approximation (VSA) introduces curvature. Comparing with Direct Numerical Simula...

PURPOSE There are currently no consistently effective treatments for the excessive collagen produced by keloid fibroblasts. Previously, we reported that heat shock protein 70 (Hsp70) is up-regulated in keloid fibroblasts and keloid tissue. We, therefore, investigated whether Hsp70 is related to excessive collagen production in keloid fibroblasts. MATERIALS AND METHODS We inhibited Hsp70 in ke...

Ocean acidification is an ongoing threat for marine organisms due to the increasing atmospheric CO(2) concentration. Seawater acidification has a serious impact on physiologic processes in marine organisms at all life stages. On the other hand, potential tolerance to external pH changes has been reported in coral larvae. Information about the possible mechanisms underlying such tolerance respon...