The termination of activation signals is a critical step in the control of the immune response; perturbation of inhibitory feedback pathways results in profound immune defects culminating in autoimmunity and overwhelming inflammation. FcgammaRIIB receptor is a well described inhibitory receptor. The ligation of B-cell receptor (BCR) and FcgammaRIIB leads to the inhibition of B-cell activation. ...

We report about a hierarchical design for extracting ship features and recognizing ships from SAR images, and which will eventually feed a multisensor data fusion system for airborne surveillance. The target is segmented from the image background using directional thresholding and region merging processes. Ship end-points are then identified through a ship centerline detection performed with a ...

Radiation pressure from the absorption and scattering of starlight by dust grains may be a crucial feedback mechanism in starburst galaxies and the self-gravitating parsec-scale disks that accompany the fueling of active galactic nuclei. I review the case for radiation pressure in both optically-thin and highly optically-thick contexts. I describe the conditions for which Eddington-limited star...

Introduction Biomass energy has received much attention in recent years. We now use about one third of the U.S. corn crop for biofuels. More recently, attention has focused on cellulosic resources—dedicated energy crops like switchgrass, miscanthus, and corn stover. Now the question has been raised concerning the economics of collecting just the corn cobs for energy instead of the stover. This ...

In recent years a great deal of research efforts in ship hydromechanics have been devoted to practical navigation problems in moving larger ships safely into existing harbours and inland waterways and to ease congestion in existing shipping routes. The starting point of any navigational or design analysis lies in the accurate determination of the hydrodynamic forces generated on the ship hull m...

The inositol phosphatases phosphatase and tensin homologue (PTEN) and Src homology 2 domain-containing inositol phosphatase (SHIP) negatively regulate phosphatidylinositol-3-kinase (PI3K)-mediated growth, survival, and proliferation of hematopoietic cells. Although deletion of PTEN in mouse T cells results in lethal T cell lymphomas, we find that animals lacking PTEN or SHIP in B cells show no ...

With the rapid development of spaceborne synthetic aperture radar (SAR) and the increasing need of ship detection, research on adaptive ship detection in spaceborne SAR imagery is of great importance. Focusing on practical problems of ship detection, this paper presents a highly adaptive ship detection scheme for spaceborne SAR imagery. It is able to process a wide range of sensors, imaging mod...

In this paper, we analyze the state-of-the-art replacement policy based on Signature-Based Hit Prediction (SHiP). While we observe that the proposed SHiP implementation improves performance over the LRU policy on all configurations, we identify three areas of improvement. First, the policies for updating the counters in the Signature History Counter Table (SHCT) can be modified. Second, a broad...