typhoid fever is an endemic disease in iran and other developing countries. this disease has gradually become resistant to the first line of drugs, and because of this resistancy we have studied a new alternative drug (cefixime) on typhoid fever patients and compared it's effectiveness with chloramphenicol. for this purpose, by a randomized clinical trial in emam khomeini hospital between ...

background: lassa fever is an acute, virulent viral haemorrhagic illness with high morbidity and mortality rates. its awareness remain low in sub urban or rural community. this study was carried out to assess the awareness of lassa fever of a rural community in the south western part of nigeria. methodology: a descriptive cross sectional study of 122 respondents prior to a sensitization seminar...

since 1999, many cases of crimean-congo hemorrhagic fever have been reported from different parts of iran. this study intended to define cchf seroprevalence, incidence rates, and the most important risks in sistan- baluchestan province, iran. using cluster sampling with probability proportional to size, 310 subjects were selected from various districts of zahedan and zabol in the northern part ...

background : bovine ephemeral fever (befv) is an arthropod-borne disease of cattle and water buffaloes. befv occurs seasonally in tropical, subtropical and temperate regions of africa, asia and australia. it has been known for the past decades in iran based on clinical signs but lack of an accurate diagnosis has made the real feature of disease obscured. this is the first scientific report on i...

background: crimean-congo hemorrhagic fever (cchf) is a disease characterized by serious course, including acute viral fever, ecchymosis, thrombocytopenia, liver dysfunction and high rate of mortality. hypoxia inducible factor-1α (hif-1α) and vascular endothelial growth factor-a (vegf-a) play an important role both in the inflamma­tory process and plasma leakage. the aim of this study was to de...

background: the mainstay of diagnosis of relapsing fever (rf) is demonstration of the spirochetes in giemsa-stained thick blood smears, but during non fever periods the bacteria are very scanty and rarely detected in blood smears by mi­cros­copy. this study is aimed to evaluate the sensitivity of different methods developed for detection of low-grade spi­ro­chetemia. methods: animal blood sampl...

objective(s):familial mediterranean fever (fmf) is an autosomal recessive disorder characterized by recurrent episodes of fever accompanied by peritonitis, pleurisy, and arthritis. fmf affects mainly mediterranean populations and is caused by mutations in the familial mediterranean fever (mefv) gene. the aim of this study was to identify the frequency and distribution of mefv mutations in irani...

the genus ebola virus first was recognized in 1976, when two outbreaks occurred in zaire and sudan. ebola virus disease (evd) is a highly contagious disease that can affect both human and nonhuman primates: zaire ebolavirus (zebov), sudan ebolavirus (sebov), côte d’ivoire ebolavirus (cebov), bundibugyo ebolavirus (bebov) and reston ebolavirus (rebov) are five members of the filoviridae family t...