Background. DNA adenine methylation plays an important role in several critical bacterial processes including mismatch repair, the timing of DNA replication and the transcriptional control of gene expression. The dependence of bacterial virulence on DNA adenine methyltransferase (Dam) has led to the proposal that selective Dam inhibitors might function as broad spectrum antibiotics. Methodology...

We examine how historic flooding in 2011 affected the geomorphic adjustments created by dam regulation along the approximately 120 km free flowing reach of the Upper Missouri River bounded upstream by the Garrison Dam (1953) and downstream by Lake Oahe Reservoir (1959) near the City of Bismarck, ND, USA. The largest flood since dam regulation occurred in 2011. Flood releases from the Garrison D...

This study investigated whether the prenatal maternal environment in dairy cattle influences the postnatal milking performance of the resulting daughters and grand-daughters. Linear mixed models were used to analyse whole season milk production from ∼ 46,000 Jersey and ∼ 123,000 Holstein Friesian cows in their 1st and 2nd lactations. Variation in the prenatal environment was associated with a s...

Indian Himalayan basins are earmarked for widespread dam building, but aggregate effects of these dams on terrestrial ecosystems are unknown. We mapped distribution of 292 dams (under construction and proposed) and projected effects of these dams on terrestrial ecosystems under different scenarios of land-cover loss. We analyzed land-cover data of the Himalayan valleys, where dams are located. ...

The World Commission on Dams (WCD) report documented a number of social and environmental problems observed in dam development projects. The WCD gave particular emphasis to the challenges of properly resettling populations physically displaced by dams, and estimated the total number of people directly displaced at 40-80 million. Less attention has been given, however, to populations living down...

Satellite Synthetic Aperture Radar Interferometry (InSAR) techniques and, specifically, Advanced Differential InSAR techniques (A-DInSAR) are becoming, in last years, a powerful tool for the investigation of ground and structure deformations, also thanks to new space missions with last generation sensors able to provide high spatial resolution (about 3x3 m), high displacement accuracy and high ...

Flood disasters cause massive loss of human lives and immense damage to the infrastructure and economic activities, not only in Turkey but also all over the world. Governments consider several long-term and short-term precautions for flood control. The numerical simulation of dam-break problems could be accomplished with geographic information systems and innovation maps. Spread of the flood wa...

Aseismic safety of dam involves people’s lives and properties, even has a great impact on national economic development. The key to this project is to have a fairly complete fluid-structure interaction (FSI) theory and a calculation method with a good accuracy. Therefore, focused on the FSI dynamic problem of gravity dam under seismic action, this paper presented the non-linear 2.5D dynamic the...

The apparent decline in the number of Nile crocodiles present in the Loskop Dam prompted a study to determine the number, size and distribution of Nile crocodiles now present in the reservoir. The number of crocodiles in the Loskop Dam was surveyed using aerial counts and spotlight counts. Surveys revealed the presence of a very low total number of crocodiles and also a poor distribution of cro...

U.S. Day-Ahead Markets (DAMs) for wholesale electric power managed by Independent System Operators (ISOs) encompass more than 60% of U.S. generating capacity. The current design of these DAMs encourages a focus on decisions that minimize immediate net costs without explicit consideration of pre-DAM and post-DAM decision opportunities. This study proposes a practical DAM reformulation that enabl...