BACKGROUND AND OBJECTIVES Factor XI deficiency is a rare hematologic disorder. Hemophilia C (factor XI deficiency) affects both genders and it is usually asymptomatic, manifesting only as postoperative hemorrhage. It is an autosomal recessive, homozygous or heterozygous, disorder, and its severity depends on the levels of factor XI. The objective of this report was to present the anesthetic str...

Having a healthy life is the right of every human being. The State has to help people live and support suffering from any disease. In this article, researcher focuses on one diseases called Hemophilia. Hemophilia bleeding genetic disorder. It included in Rights People with Disability Act, 2016. highly neglected There no research legal perspective topic. This paper will understand hemophilia gap...

Acquired factor VIII deficiency (acquired hemophilia A) is a rare condition characterized by the acquisition of autoantibodies that affect the clotting activity of factor VIII (fVIII). The most common manifestation in affected patients is a hemorrhagic diathesis. This disorder is associated with autoimmune diseases, pregnancy, postpartum period, drugs, and malignancy. Management of this conditi...

Hemophilia is an X-linked recessive bleeding disorder caused by deficiency of FVIII (hemophilia A) or FIX (hemophilia B). Mutations in the FVIII or FIX genes, both located on the long arm of the X chromosome, are detectable in the majority of cases of hemophilia A or B, respectively. During normal hemostasis, FVIII and FIX form an enzymatic complex; thus, deficiency of either protein leads to a...

Hemophilia A (HA) is an X-linked genetic hemorrhagic disorder resulting from a deficiency of blood coagulation factor VIII. The mutation type within the factor VIII gene may influence the clinical severity of hemophilia. It has also recently been suggested that the clinical phenotype of HA is influenced by co-inheritance of the factor V G1691A mutation or the factor II G20210A variant. This cli...

background: treating a chronic disease such as hemophilia is to improve the symptoms and quality of life (qol) of the patients. this study aimed to study the quality of life among hemophilic children and compare the quality of life between patients receiving prophylactic or on demand treatments. materials and methods: in this descriptive-comparative study, we enrolled 60 patients from three mai...

background and aim: hemophilia is among the most prevalent and the most serious coagulation disorders which causes different problems for both the afflicted children and their families. this study was undertaken to investigate the relationship between coping strategies and quality of life (qol )among the principal caregivers of children with hemophilia. methods: this correlational study was con...

Improvements in hemophilia care and antiviral treatments have resulted in increases in median life expectancy for persons with congenital hemophilia A and B. Currently, 2% of hemophilia A and B patients surveyed in US comprehensive hemophilia treatment centers are 65 years of age or older and 15% are 45 years or older. Many of the complications of hemophilia, including intracranial hemorrhage, ...