نتایج جستجو برای: severe congenital neutropenia

تعداد نتایج: 443969  

Journal: :Haematologica 2014
Cornelia Zeidler Ulrike A H Grote Anna Nickel Beate Brand Göran Carlsson Emília Cortesão Carlo Dufour Caroline Duhem Gundula Notheis Helen A Papadaki Hannah Tamary Geir E Tjønnfjord Fabio Tucci Jan Van Droogenbroeck Christiane Vermylen Jaroslava Voglova Blanca Xicoy Karl Welte

Long-term granulocyte-colony stimulating factor treatment has been shown to be safe and effective in severe chronic neutropenia patients. However, data on its use during pregnancy are limited. To address this issue, we analyzed all pregnancies reported to the European branch of the Severe Chronic Neutropenia International Registry since 1994. A total of 38 pregnancies in 21 women with chronic n...

آموزگار, محمد حسن, خاتمی, سید محمد, مهاجرزاده, لیلا,

  Bacterial infection following major burn injury leads to neutrophile dysfunction and neutropenia which results in serious sepsis. Administration of graolocyte-colon specific factor (G-CSF) is useful for treatment of neutropenia and decreasing the complications of severe infection following burn injuries. A 2- year old boy with major burn injury, despite administration of broad spectrum antibi...

Journal: :Blood 2000
C Zeidler K Welte Y Barak F Barriga A A Bolyard L Boxer G Cornu M J Cowan D C Dale T Flood M Freedman H Gadner H Mandel R J O'Reilly U Ramenghi A Reiter R Skinner C Vermylen J E Levine

Severe congenital neutropenia (CN) (Kostmann syndrome) is a hematologic disorder characterized by a maturation arrest of myelopoiesis at the promyelocyte/myelocyte stage of development. This arrest results in severe neutropenia leading to absolute neutrophil counts (ANC) below 0.2 x 10(9)/L associated with severe bacterial infections from early infancy. Data on over 300 patients with CN collect...

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