نتایج جستجو برای: severe asthma
تعداد نتایج: 386339 فیلتر نتایج به سال:
Severe asthma is a heterogeneous disease. Identification of specific sub-phenotypes of asthma may further improve our understanding of its pathophysiology. The genetic and environmental elements that may be important in the development of the disease are poorly understood, but it appears that the pathophysiological background of severe asthma includes both allergic and non-allergic elements. In...
Background: Asthma is a multifactorial disease and its severity varies with the inflammatory grade. There are conflicting reports about the roles of trace elements in asthma. This study examined the effects of zinc (Zn), copper (Cu), and selenium (Se) concentrations in sera of patients with allergic asthma attending Ghaem Hospital, Mashhad, Iran. Methods: Forty-nine patients, aged 10 to 50 y...
BACKGROUND Tumour necrosis factor alpha (TNFalpha) is a major therapeutic target in a range of chronic inflammatory disorders characterised by a Th1 type immune response in which TNFalpha is generated in excess. By contrast, asthma is regarded as a Th2 type disorder, especially when associated with atopy. However, as asthma becomes more severe and chronic, it adopts additional characteristics i...
Asthma is a cause of severe morbidity and mortality in the United States. Severe acute asthma accounts for over one million emergency room visits per year (1). The vast majority of patients presenting with acute asthma can be successfully managed with β2-agonist bronchodilators, corticosteroids, and oxygen. Despite maximal medical therapy, it is estimated that 1– 3% of patients with severe asth...
Persistent asthma has long been treated with inhaled corticosteroids (CSs), as the mainstay of therapy. However, their efficacy in patients with more severe disease is limited, which led to the incorporation of poor response to ICSs (and thereby use of high doses of ICS) into recent definitions of severe asthma. Several studies have suggested that severe asthma might consist of several differen...
Background: Tumour necrosis factor a (TNFa) is a major therapeutic target in a range of chronic inflammatory disorders characterised by a Th1 type immune response in which TNFa is generated in excess. By contrast, asthma is regarded as a Th2 type disorder, especially when associated with atopy. However, as asthma becomes more severe and chronic, it adopts additional characteristics including co...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید