This report describes a case of severe hypernatremia with a serum sodium concentration of 188.1mmol/L caused by exogenous salt intake. A 26-year-old man diagnosed with Crohn's disease 5 years previously visited our clinic due to generalized edema and personality changes, with aggressive behavior. He had compulsively consumed salts, ingesting approximately 154 g of salt over the last 4 days. Des...

A s a rule of thumb in clinical medicine, the serum sodium concentration decreases by 1.6 mEq/l for every 100 mg/dl increase in glucose concentration due to water shifts from the intracellular to the extracellular compartment (1). This correction factor is based on theoretical considerations and has not been well validated. An experimental study in healthy subjects found significantly greater d...

BACKGROUND Numerous studies have shown that long term treatment with anticonvulsants may be an important risk factor for the onset of atherosclerosis, or worsening of its symptoms. There are many contradictory reports regarding these effects. OBJECTIVES We performed a systematic review and meta-analysis of the published studies in order to see whether the atherogenic outcomes could be related...

An 83-year-old man admitted for weakness, lethargy, and mental status changes was found to have human immunodeficiency virus (HIV) disease and cryptococcal meningitis. His hospital course was complicated by worsening hyponatremia (sodium < 136 mEq/L). By hospital day 6, the patient’s serum sodium had declined to 127 mEq/L from his admission level of 133 mEq/L. The initial impression was that th...

how to cite this article: heydarian f, rezaeian a. relationship between changes in serum sodium level and seizures occurrence in children with hypernatremic dehydration. iran j child neurol. 2013 autumn;7(4): 35- 40.   objective to assess any relationship between serum sodium changes and seizure occurrence in children aged 2 months to 5 years with hypernatremic dehydration.   materials & method...

Background Colonoscopy is the gold standard investigation for assessing of the intra-luminal colorectal pathology. Effective bowel preparation contributed efficient visualizing of the colon. Osmotic laxatives such as sodium phosphate (NaP) are commonly used for colonic preparation for colonoscopy. A meta-analysis suggested that NaP offered a more effective and more readily completed preparation...

BACKGROUND Hyponatremia predicts poor prognosis in patients with acute heart failure (AHF). However, the association of the severity of hyponatremia and changes of serum sodium levels with long-term outcome has not been delineated. METHODS AND RESULTS The study population was drawn from the HARVEST registry (Heart Failure Registry of Taipei Veterans General Hospital), so that patients hospita...

This study evaluated the usage of Beckman Coulter AU680 analyzers for measurement of TCO 2 in horse serum, and the effect of sodium bicarbonate administrations on serum TCO 2 levels in resting horses. Treatment of horses with sodium bicarbonate did not result in any adverse events. Mean TCO 2 concentration was significantly higher from 1 to 8 h in the sodium bicarbonate-treated horses compared ...

Hyponatremia is a very commonly encountered clinical entity with potentially dangerous effects and for which many precipitating factors have been identified. We present a case of valproic acid (VPA) overdose causing profound hyponatremia, with one of the lowest serum sodium levels ever documented in literature. A 54-year-old woman with hypothyroidism, hypertension and bipolar disorder presented...