Roerink et al. (1) raise important and potential methodological biases that could have accounted for our finding regarding elevated TGF-β levels in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) (2). Here, we provide additional information as requested by Roerink et al. (1) that supports that the elevation of TGF-β in patients with ME/CFS is most likely to be rooted i...

OBJECTIVE Television, Internet and print media are saturated with advertisements for unhealthy food that use marketing tactics aimed to build long-term brand loyalty and 'relationships' with children. While research in this area has largely focused on television, the current study examines children's responses to relationship-building marketing communications found in popular children's magazin...

ing away from responsibility factor allows us to simplify the MMR model laid out in section 2. The value of the outcome x to the subject and counterfactual outcome y to the “other” can now be written as: V i (x, y) = u(x) + G i ( x y ) [5] for i=0,1 where G is the function relevant in the private and G 1 in the social environments. Using simplified version of MMR our hypotheses for the BOLD sig...

Query-specific summarization of multiple documents is a useful task in the current day context of the WWW, that is containing huge amount of information. When different summarizers have access to different sets of documents for a query, generating a summary of the summaries produced by the multiple summarizers becomes an interesting and useful task. In this paper, we propose an efficient soluti...

Michigan-Dearborn. Prof. Su dedicated much of his precious time in giving guidance and provide leadership for this work. He always kept a good track of the progress by arranging weekly and monthly group meetings. His helpful advices, corrections and guidance helped steered me in the right the direction and finished this work successfully. I would also like to thank my fellow lab colleagues. The...

OBJECTIVE to analyze the effect of the modifications in the Cockcroft-Gault equation for creatinine clearance rate determination (CrCl) and its concordance with the real value determined from 24-hours urine collection in a sample of Latin American patients hospitalized in San José de Costa Rica. METHOD an observational, retrospective study, with patients submitted to a 24-hour urine collectio...

Restricting food intake to a level below that consumed voluntarily (85%, 70% and 50% of the ad libitum energy intake for 3 or 30 days) and re-feeding ad libitum for 48 h results in an increase of malic enzyme (ME) gene expression in rat white adipose tissue. The increase of ME gene expression was much more pronounced in rats maintained on restricted diet for 30 days than for 3 days. The changes...

The anesthetic effect of a combination of medetomidine, midazolam and butorphanol (Me-Mi-Bu) was evaluated in healthy cynomolgus monkeys. The Me-Mi-Bu combination was intramuscularly administered as follows: Dose 1, Me 0.015 mg/kg-Mi 0.1 mg/kg-Bu 0.15 mg/kg; Dose 2, Me 0.02 mg/kg-Mi 0.15 mg/kg-Bu 0.2 mg/kg; and Dose 3, Me 0.04 mg/kg-Mi 0.3 mg/kg-Bu 0.4 mg/kg. The combination rapidly induced imm...

iSTART is an intelligent tutoring system (ITS) designed to improve students’ reading comprehension. Previous studies have indicated that iSTART is successful; however, these studies have also indicated that students benefit most from long-term interactions that can become tedious and boring. A new game-based version of the system has been developed, called iSTART-ME (motivationally enhanced). I...