advanced glycation end-products (ages) are formed by non-enzymatic reaction between reducing sugar and protein. ages play important roles in pathogenesis of diabetic, aging complications, endothelial dysfunction and neurological diseases such as the alzheimer’s disease. therefore compounds that prevent the glycation reaction are purported to have therapeutic effect on patients with diabetes and...

serum fatty acids on 30 healthy lranian women were detemined by a gas chromatographic method. oleic and stearic acids were used as standards. the mean values were myristic acid 5. 7% , palmitic acid 43% , palmitoleic acid 5.3% , stearic acid 8% , oleic acid 21. 3% and linleic acid 16.4% of total fatty acid serum contents.

brucellosis is an endemic disease in our country. neurobrucellosis occurs in 5 to 10% of cases, and can present at any stage of of the disease. this study was undertaken to evaluate clinical, epidemiological and paraclinical aspects of brucellosis with and without neurological manifestations. data of 30 patients, 15 cases with nervous system involvement (neurobrucellosis) and 15 cases without n...

the bulk of our knowledge on immunosuppression in malnutrition comes from the experiments done on cell-mediated immunity. however, malnutrition-induced modifications of humoral immunity have been less understood. the objective of this study was to determine the effects of acute protein-energy malnutrition on serum levels of immunoglobulins and their subclasses in murine models. male and female ...

backgrounds and aims: thyroid hormones have a crucial physiological role to maintain balance of metabolism of body. thyroid hormones have an important role in metabolism and proliferation of blood cells. thyroid gland also has a vital influence on erythropoiesis by induction of erythropoietin secretion and proliferation of erythroid progenitors. in the present study, it was tried to evaluate th...

background and aims. oral lichen planus (olp) is an immunologic disorder. a large number of studies have reported that lipid rafts have a key role in receptor signaling of lymphocytes. here, we explore the potential of lipid rafts as targets for the development of a new class of agents to down-modulate immune responses and treat autoimmune diseases. materials and methods. the present cross-sect...

conclusions diabetes may be caused by toxoplasma gondii. presence of t. gondii in the pancreas at the same time could directly undermines the pancreas cells. when β cells are destroyed, insulin secretion would then be affected. probably the destruction of t. gondii affects nervous system and damages pancreatic cells leading to increased risk of diabetes. results the prevalence of igg antibodies...

background: preeclampsia is a pregnancy multisystem disorder of unknown etiology. it is a significant cause of maternal and fetal morbidity and mortality. objectives: due to the significant role of magnesium in physiological regulation of blood pressure, this study was conducted to measure the level of magnesium in pre-eclampsia and control groups since the beginning of the pregnancy. materials...

this study was aimed to evaluate the effects of diets containing some hot and coldtemperament herb seeds according to iranian traditional medicine (itm) on some metabolicparameters in acute (24 h) and sub-acute (7 day) experiments that were performed on rats. foreach experiment, effects of diets containing 10% herb seeds in category of hot (anise, fennel,ajowan) and cold (cucumber, watermelon, ...

introduction and aims: both observational and experimental studies have shown that higher selenium status reduces the risk of upper gastrointestinal cancers in selenium deficient populations. recent cancer registry data have shown very different rates of esophageal cancer (ec) and gastric cancer (gc) in four provinces of iran, namely ardabil, mazandaran, golestan, and kerman. the aim of this st...