نتایج جستجو برای: sequence alignment

تعداد نتایج: 465792  

Journal: Mycologia Iranica 2019

Mycophenolic acid (MPA) is a fungal metabolite possessing antiviral, antifungal, antibacterial, antitumor and anti-psoriasis activities. It is being used as an immunosuppressive agent in kidney, heart and liver transplantation patients. In the presence of MPA, the proliferation of the B and T lymphocytes is inhibited. The MPaB and MPaE genes reside in a 25 kb gene cluster in t...

2005
M. F. Omar R. A. Salam R. Abdullah N. A. Rashid

Proteins or genes that have similar sequences are likely to perform the same function. One of the most widely used techniques for sequence comparison is sequence alignment. Sequence alignment allows mismatches and insertion/deletion, which represents biological mutations. Sequence alignment is usually performed only on two sequences. Multiple sequence alignment, is a natural extension of two-se...

Journal: :Nucleic Acids Research 2006
Timo Lassmann Erik L. L. Sonnhammer

Obtaining high quality multiple alignments is crucial for a range of sequence analysis tasks. A common strategy is to align the sequences several times, varying the program or parameters until the best alignment according to manual inspection by human experts is found. Ideally, this should be assisted by an automatic assessment of the alignment quality. Our web-site http://msa.cgb.ki.se allows ...

2007

When a group of aligned sequences shows significant similarity to each other, as described in Chapters 4 to 6, this can usually be taken as evidence that they are the result of divergent evolution from a common ancestral sequence. In this case, the sequence alignment will contain traces of the evolutionary history of these sequences. It is possible to infer this history by complex analysis of a...

Journal: :Bioinformatics 2005
Olivier Pible Gilles Imbert Jean-Luc Pellequer

SUMMARY Improving and ascertaining the quality of a multiple sequence alignment is a very challenging step in protein sequence analysis. This is particularly the case when dealing with sequences in the 'twilight zone', i.e. sharing < 30% identity. Here we describe INTERALIGN, a dedicated user-friendly alignment editor including a view of secondary structures and a synchronized display of carbon...

Journal: :SIAM Journal on Applied Mathematics 1988

Journal: :Journal of Computer Science 2008

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