The worldwide incidence of malignant melanoma is increasing at an alarming rate. The importance of diagnosing nodal metastatic disease has impacted significantly on the accurate staging and stratification of melanoma patients. As a minimally invasive procedure with low morbidity, sentinel lymph node mapping allows for a detailed histopathologic evaluation involving multiple sections, H&E staini...

Axillary clearance provides important prognostic information but is associated with significant morbidity. Sentinel node biopsy can provide staging .141 patients with node negative early breast cancers-tumour size less than 1.5 cm measured clinically or by imaging had guided axillary sampling (sentinel lymph node biopsy in combination with axillary sampling). Four node axillary sampling improve...

INTRODUCTION The level of lymph node involvement is the most important factor in staging colorectal cancer without metastasis. Sentinel lymph node mapping identifies the node(s) that most accurately reflect the lymph node status of patients, and intensive techniques that improve staging can be focused on these nodes. The aim of this study was to assess the efficacy of ex vivo sentinel lymph nod...

AIM The aim of this study was to present one center experience in applying the SNOLL technique to patients with suspected occult breast lesions. BACKGROUND In the last years, the widespread use of mammographic screening programs resulted in an increasing number of women with nonpalpable suspicious breast lesions requiring further examination. The new method called sentinel node and occult les...

PRIMARY PURPOSE The staging of regional nodes by means of sentinel node detection has been shown to accurately detect subclinical nodal metastases from cutaneous melanoma. On the other hand, the oncological applications of 18F-fluoro-2-deoxy-D-glucose positron emission tomography (18FDG PET) are, nowadays, firmly established. However, the sensitivity of such metabolic imaging for staging the re...

Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. (99m)Tc-radiocolloids have been the standard radiotracers used for sentinel node mapping. (99m)Tc-tilmanocept is a receptor-binding molecular imaging agent approved by the U.S. Food and Drug Administration for lymph...

.................................................................................................. 7 Introduction ............................................................................................ 9 Review of the Literature ............................................................................ 11 1. Breast Cancer Incidence and Survival ..............................................

BACKGROUND The aim of this retrospective study was to ascertain the postoperative morbidity in patients with vulvar cancer undergoing sentinel lymph node vs. complete inguinal lymph node dissection. PATIENTS AND METHODS In total 29 and 46 patients with vulvar cancer, were treated by the technique of inguinal sentinel lymph node dissection or complete inguinal lymph node dissection, respective...

It is still a matter of debate whether sentinel node biopsy might replace neck dissection in patients with clinically negative neck lymph nodes who suffer from oral squamous cell carcinoma. In 30 patients (26 male, 4 female, average age 59.4 years) with oral squamous cell carcinoma we performed ultrasound guided punction of the lymph nodes which were lymphoscintigraphically seen together with h...

The sentinel lymph node was defined as the first lymph node to receive drainage from a primary cancer. The aims of this study were to investigate the efficacy of radiocolloid lymphoscintigraphy and of the hand-held gamma probe procedure for sentinel lymph node biopsy in papillary thyroid carcinoma and to evaluate these results in clinical staging. A total of 99 consecutive papillary thyroid car...