Epigenetic mechanisms including altered DNA methylation are critical for altered gene transcription subserving synaptic plasticity and the retention of learned behavior. Here we tested the idea that one role for activity-dependent altered DNA methylation is stabilization of cognition-associated hippocampal place cell firing in response to novel place learning. We observed that a behavioral prot...

Introduction Despite the critical role of motivation in psychosocial treatment and rehabilitation, as well functional outcomes schizophrenia, service user voices are not always present setting research agendas on this topic. This is important since user’s involvement process helps prioritize questions (Wykes et al., 2015). Objectives We have begun a consultation to bridge gap between practice ‘...

This article reviews from both theoretical and numerical aspects three non-equivalent complete second-order formulations of quantum dissipation theory, in which both the reduced dynamics and the initial canonical thermal equilibrium are properly treated in the weak system-bath coupling limit. Two of these formulations are rather familiar as the time-local and the memory-kernel prescriptions, wh...

Around 10% of deep inelastic scattering (DIS) events observed at HERA at small value of the Bjorken variable x are diffractive events [1, 2], when the incoming proton stays intact losing only a small fraction xIP of its initial momentum. A large rapidity gap is formed between the scattered proton (or its low mass excitation) and the diffractive system. The ratio of diffractive to total DIS cros...

Hippocampal spatial view cells found in primates respond to a region of visual space being looked at, relatively independently of where the monkey is located. Rat place cells have responses which depend on where the rat is located. We investigate the hypothesis that in both types of animal, hippocampal cells respond to a combination of visual cues in the correct spatial relation to each other. ...

Hippocampal place cells are a model system of how the brain constructs cognitive representations and of how these representations support complex behavior, learning, and memory. There is, however, a lack of detailed knowledge about the properties of hippocampal afferents. We recorded multiple single units from the hippocampus and the medial and lateral entorhinal areas of behaving rats. Althoug...

The most common kind of collections for GIR so far are the Web and other document collections, which are mainly textual. This paper is concerned with the non-trivial relationship between reference to place in natural language (NL) and common GIR assumptions. There are two main ways in which NL texts and GIR meet: in the attempt to derive or populate geo-ontologies from text itself, and in the a...