Lead is a harmful pollutant from engine exhaust that causes free radicals and has detrimental effects on the testicular tissue. This study aimed to determine of tomato juice number Leydig cells diameter seminiferous tubules mice exposed lead acetate. Twenty-five male were divided into five groups. Mice in control (C-) group given placebos. Meanwhile, C+, T1, T2, T3 groups acetate at dose 100 mg...

The Sertoli cell is a critical somatic that initiates the development of testicular morphology and determines important parameters for spermatogenic function. blood-testis barrier, also known as barrier one tightest tissue barriers in mammalian body, an immunological to separate post meiotic germ antigens from systemic circulation. Additionally, creating unique microenvironment spermatocytes ex...

Background: Formaldehyde is a chemical that used in fixed tissues and bodies. Formaldehyde during dissection of cadaver, evaporate and be released. Studies have shown that the gas increase endogenous opioids, nitric oxide and cytokines in plasma. These impacts can affect on gonadotropin hormones. The aim of this study was to investigate possible changes in gonadotropin and epithelial cells of t...

Testicular tissue cryopreservation is the only potential option for fertility preservation in pre-pubertal boys exposed to gonadotoxic treatment. Completion of spermatogenesis after in vitro maturation is one of the future uses of harvested testicular tissue. The purpose of the current study was to evaluate the effects of vitamin A on in vitro maturation of fresh and frozen-thawed mouse pre-pub...

The area, perimeter and diameter of the seminiferous tubules in the European bison Bison bonasus (L.) were statistically higher in the animals with than in those without spermiogenesis, both among 2-year-old and 3-year-old males (p < 0.001; p < 0.001; p < 0.001).

I am writing in response to the article, “A quantitative and qualitative study of rat testis following administration of methadone and buprenorphine” by Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb & Farhad Kohan in Volume 1(1): 14-17, 2012 (1). This article is addresses an important subject, that of hypogonadism and other changes in seminiferous tubules and testis after administration of metha...

A thorough understanding of the events during mammalian spermatogenesis requires studying specific molecular signatures of individual testicular cell populations as well as their interaction in co-cultures. However, most purification techniques to isolate specific testicular cell populations are time-consuming, require large numbers of animals, and/or are only able to isolate a few cell types. ...