Scutellaria is one of the largest genera in Lamiaceae with an estimated 400–500 species a nearly worldwide distribution. Most occur N hemisphere, Caucasus and wider Irano-Turanian region housing large number taxa, many them considered endemic. We present overall phylogeny monophyletic genus based on rapidly evolving plastid regions (matK-trnK, rpl16, trnL-F). Three well-supported clades are evi...

objective: scutellaria luteo-caerulea bornm. & snit. is one of the species of genus scutellaria, within the family of the lamiaceae, that is used for immune system stimulation and antibacterial effects in traditional medicine in iran. the aims of this study were to analyze essential oils and mineral element contents of leaves of  s. luteo-caerulea in flowering stage of development. materials an...

Jelen tanulmány a Vértesalja homoki bükköseinek társulási viszonyait mutatja be 25 cönológiai felvétel alapján. Faji összetételére Fagetalia elemek magas aránya jellemző. Különösen értékes fajai Corydalis intermedia, Daphne laureola és Scutellaria columnae. A felvételek hagyományos sokváltozós statisztikai elemzések alapján elkülönülnek Belső-Somogy bükköseitől (Leucojo verno-Fagetum), Dunántúl...

Baicalein is a purified flavonoid extracted from the roots of Scutellaria baicalensis or Scutellaria radix. Although previous studies have suggested that Baicalein possesses an in vitro anti-hepatocellular carcinoma activity, its in vivo effects and mechanisms of action are still not completely understood. In this study, Baicalein at concentrations of 40-120 µM exhibited significant cytotoxicit...

Anthocyanin is the main pigment forming floral diversity. Several transcription factors that regulate the expression of anthocyanin biosynthetic genes belong to the R2R3-MYB family. Here we examined the transcriptomes of inflorescence buds of Scutellaria species (skullcaps), identified the expression R2R3-MYBs, and detected the genetic signatures of positive selection for adaptive divergence ac...

Angiogenesis, which plays a critical role during tumor development, is tightly regulated by the Sonic Hedgehog (SHH) pathway, which has been known to malfunction in many types of cancer. Therefore, inhibition of angiogenesis via modulation of the SHH signaling pathway has become very attractive for cancer chemotherapy. Scutellaria barbata D. Don (SB) has long been used in China to treat various...

BACKGROUND Flavonoid-rich extracts from the mature roots of Scutellaria baicalensis have been shown to exhibit antiproliferative effects on various cancer cell lines. We assessed the ability of an ethanolic extract of S. baicalensis root to inhibit the proliferation of malignant glioma cells. METHODS Cell lines derived from primary and recurrent brain tumors from the same patient and cells se...

We determined the in vitro antioxidant activity of methanolic extracts from the shoots and roots of Scutellaria species (S. altissima and S. alpina) against the action of strong oxidants: hydrogen peroxide (H2O2) and H2O2+Fe(2+) (donor of hydroxyl radicals) on plasma proteins and lipids. Lipid peroxidation in human plasma was measured by the level of thiobarbituric acid reactive species (TBARS)...

Shi Yu, 2, 3 Peng Xu, 2 Xiaodong He, 2 Min Liu, 2 Jin Wang, 2 and Mingsheng Zhan 2, ∗ State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences Wuhan National Laboratory for Optoelectronics, Wuhan 430071, China Center for Cold Atom Physics, Chinese Academy of Sciences, Wuhan 430071, China Graduate Univers...