The emergence of regenerative medicine has raised the hope of treating an extraordinary range of disease and serious injuries. Understanding the processes of cell proliferation, differentiation and pattern formation in regenerative organisms could help find ways to enhance the poor regenerative abilities shown by many other animals, including humans. Recently, planarians have emerged as an attr...

ABSTRACT As the planarian research community expands, need for an interoperable data organization framework tool building has become increasingly apparent. Such software would streamline annotation and enhance cross-platform cross-species searchability. We created Planarian Anatomy Ontology (PLANA), extendable relational of defined Schmidtea mediterranea (Smed) anatomical terms used in field. A...

Regeneration requires the precise integration of cues that initiate proliferation, direct differentiation, and ultimately re-pattern tissues to the proper size and scale. Yet how these processes are integrated with wounding responses remains relatively unknown. The freshwater planarian, Schmidtea mediterranea, is an ideal model to study the stereotyped proliferative and transcriptional response...