Intestinal Schistosomiasis is a serious disease and is commonly produced by S. mansoni and japonicum. The presence of viable ova of the organism in the colon elicits inflammation, formation of granuloma, ulcers, haemorrhage and colonic fibrosis with subsequent longterm sequelae. Schistosoma mansoni is endemic in the Middle East, Africa, Central and South America. This is a case of a Nigerian wi...

Schistosomiasis, or bilharzias, is a neglected disease that remains a considerable public health problem in tropical and subtropical regions. This parasitic disease is the most important human helminth infection in terms of morbidity and mortality and is a growing concern worldwide. It is estimated that more than 200 million people have been infected and that 779 million are at risk of infectio...

BACKGROUND Schistosomiasis japonica still remains of public health and economic significance in China, especially in the lake and marshland areas along the Yangtze River Basin, where the control of transmission has proven difficult. In the study, we investigated spatio-temporal variations of S. japonicum infection risk in Anhui Province and assessed the associations of the disease with key envi...

Schistosomiasis is a parasitic disease acquired through contact with contaminated freshwater. The definitive hosts are terrestrial mammals, including humans, some Schistosoma species crossing the animal-human boundary zoonotic transmission. An estimated 12 million people live at risk of schistosomiasis caused by japonicum and mekongi , largely in World Health Organization’s Western Pacific Regi...

BACKGROUND Schistosomiasis is a helminthic disease that affects more than 200 million people. An effective vaccine would be a major step towards eliminating the disease. Studies suggest that T follicular helper (Tfh) cells provide help to B cells to generate the long-term humoral immunity, which would be a crucial component of successful vaccines. Thus, understanding the biological characterist...

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causal agent of Kaposi's sarcoma (KS), a common cancer in patients with acquired immunodeficiency syndrome. The risk factors for KSHV infection have been extensively studied for Western countries but remain largely undefined for other parts of the world. Schistosomiasis, caused by Schistosoma japonicum infection, was recently identified ...

Technical Appendix Technical Appendix Figure 1. Places of residence in Peninsular Malaysia (left) of the schistosomiasis-infected Orang Asli from the 1970s. The origin of the patient from the current report is marked with a red X in a circle; previous cases are marked with green Xs without circles. Three cases in persons also infected with Schistosoma japonicum–like eggs in Sabah, Malaysian Bor...

BACKGROUND Current diagnostic methods for Schistosoma japonicum infection are insensitive for low-density infections. Therefore, a new diagnostic assay based on recombinase polymerase amplification (RPA) technology was established and assessed for field applification. METHODS The S.japonicum RPA assay was developed to target highly repetitive retrotransposon SjR2 gene of S japonicum, and its ...

Human schistosomiasis is caused by the genus Schistosoma. Its prevalence and morbidity are highest among schoolchildren, adolescents, young adults. It prevalent in poor communities without access to safe drinking water adequate sanitation. The agents of etiology these diseases Schistosoma mansoni, haematobium, guineensis, intercalatum, japonicum, mekongi. Symptoms include anemia, stunting, feve...