background praziquantel, an antischistosomal compound, is used as first-line drug for chemotherapy of schistosoma japonicum since 1984. in this article, we conducted a systematic review and mete-analysis to evaluate the efficacy and safety of different dosages of praziquantel (pzq) for treatment of schistosoma japonicum. evidence acquisition: a number of six articles published in peer-reviewed ...

Soil-transmitted helminths and schistosomiasis are among seventeen WHO prioritized neglected tropical diseases that infect humans. These parasitic infections can be treated using single-dose, safe and often donated drugs. Ethiopia successfully mapped the distribution of these infections nationwide. According to the mapping there are an estimated 38.3 million people living in schistosomiasis end...

Introduction: According to the World Health Organization (WHO), helminth control could contribute to achieving 7 Millennium Development Goals (MDGs). The present study evaluated the impact of deworming on the infection rate of schistosomiasis in Sumidouro, Brazil and the consequences for the MDGs. Methods: The whole population of this area was invited to ...

BACKGROUND Given the restricted distribution of Schistosoma mekongi in one province in Lao People's Democratic Republic (Lao PDR) and two provinces in Cambodia, together with progress of the national control programmes aimed at reducing morbidity and infection prevalence, the elimination of schistosomiasis mekongi seems feasible. However, sensitive diagnostic tools will be required to determine...

Human schistosomiasis is one of the most common Neglected Tropical Diseases (NTDs); it is an intravascular parasite caused by the trematode blood fluke (Schistosoma). Most human infections are caused by S. haematobium, S. mansoni, and S. japonicum. An estimated total of 237 people are infected worldwide, and 732 million people are at risk of being infected. In the Middle East and North Africa (...

Over the last sixty years advances have been made in the control of schistosomiasis in P.R. China. There are, however, difficult challenges still to be met. This paper looks at the extent to which the health system offers a positive environment for the control of the disease. It starts by tracing three phases in schistosomiasis control: disease elimination strategy through snail control (1950s-...

Schistosomiasis japonica is a serious communicable disease and a major disease risk for more than 30 million people living in the tropical and subtropical zones of China. Infection remains a major public health concern despite 45 years of intensive control efforts. It is estimated that 865,000 people and 100,250 bovines are today infected in the provinces where the disease is endemic, and its t...

BACKGROUND Human waste is used as an agricultural fertilizer in China and elsewhere. Because the eggs of many helminth species can survive in environmental media, reuse of untreated or partially treated human waste, commonly called night soil, may promote transmission of human helminthiases. METHODOLOGY/PRINCIPAL FINDINGS We conducted an open cohort study in 36 villages to evaluate the associ...

Schistosomes are parasitic flatworms that cause schistosomiasis, a Neglected Tropical Disease affecting at least 249 million people worldwide. It is the most important waterborne disease in America introduced to this continent during the time of the African slave trade. Of the seven species that infect humans, only Schistosoma mansoni is present in America. Schistosomiasis is endemic in Brazil,...