The understanding of the mechanisms underlying eosinophil migration into tissue is an essential step in the development of novel therapies aimed at treating allergic diseases where eosinophil recruitment and activation are thought to play an essential role. In this study, we have examined the effects of the in vivo administration of stem cell factor (SCF) on eosinophil recruitment and tested wh...

BACKGROUND The effects of topical application of sucralfate (SCF) on the tissue content of MUC-2 protein have not yet been evaluated in experimental models of diversion colitis. AIM To measure the tissue content of MUC-2 protein in the colonic mucosa diverted from fecal stream submitted to the SCF intervention. METHODS Thirty-six rats underwent derivation of intestinal transit through proxi...

Production of hematopoietic growth factors by endothelial cells plays a pivotal role during inflammatory processes. Stem cell factor (SCF) is known to be expressed constitutively in endothelial cells. To investigate the regulation of this cytokine expression by inflammatory stimuli, we cocultured human umbilical vein endothelial cells (HUVEC) with various gram-negative bacterial strains (Escher...

BACKGROUND Slow coronary flow (SCF) is characterized by delayed opacification of epicardial coronary vessels. SCF can cause ischemia and sudden cardiac death. We investigated the association between presence and extent of SCF, and cardiovascular risk factors and hematologic indices. METHODS In this study, 2467 patients who received coronary angiography for suspected or known ischemic heart di...

In the evolution of wireless networks such as wireless sensor networks, mobile ad-hoc networks, and delay/disruption tolerant networks, the Store-Carry-Forward (SCF) message relaying paradigm has been commonly featured and studied with much attention. SCF networking is essential for offsetting the deficiencies of intermittent and range limited communication environments because it allows moving...

Mast cells are thought to contribute significantly to the pathology and mortality associated with anaphylaxis and other allergic disorders. However, studies using genetically mast cell-deficient WBB6F1-KitW/KitW-v and congenic wild-type (WBB6F1-+/+) mice indicate that mast cells can also promote health, by participating in natural immune responses to bacterial infection. We previously reported ...

Stem cell factor (SCF) enhances normal hematopoiesis. We examined its effect in vitro on bone marrow and blood progenitors from patients with inherited bone marrow failure syndromes, including 17 patients each with Diamond-Blackfan anemia (DBA) and Fanconi's anemia (FA), 3 with dyskeratosis congenita (DC), and 1 each with amegakaryocytic thrombocytopenia (amega) and transient erythroblastopenia...

This paper presents a method of improving the quality of subcategorization frames (SCFs) acquired from corpora in order to augment a lexicon of a lexicalized grammar. We first estimate a confidence value that a word can have each SCF, and create an SCF confidence-value vector for each word. Since the SCF confidence vectors obtained from the lexicon of the target grammar involve co-occurrence te...