Introduction: The outcome for patients with mantle cell lymphoma (MCL) has drastically improved new treatments directed towards the tumor immune microenvironment, where macrophages play an important role. In MCL, presence of M2 defined by CD163 expression in diagnostic biopsies been associated a worse prognosis. An alternative way to assess abundance is measuring level soluble serum (sCD163). M...

This study aimed to determine the role of soluble costimulatory molecules in aging and association with presence comorbid aged individuals. Thirty-two elderly twenty healthy subjects were included this study. The sCD28, sCD80, sCD86, sCD163, sCTLA4 measured using ELISA. was documented from medical records. Charlson Comorbidity Index (CCI) evaluate survival/mortality risk for subjects. levels ma...