Covalent labeling of solvent exposed amino acid residues using chemical reagents/crosslinkers followed by mass spectrometric analysis can be used to determine the solvent accessible amino acids of a protein. A variety of chemical reagents containing cleavable bonds were developed to label abundantly found lysine residues on the surface of protein. To achieve efficient separation of labeled pept...

Humans may be exposed to engineered silica nanoparticles (SiO2-NPs) but potential adverse effects are poorly understood, in particular in relation to cellular effects and modes of action. Here we studied effects of SiO2-NPs on cellular function in human hepatoma cells (Huh7). Exposure for 24 h to 10 and 50 μg/ml SiO2-NPs led to induction of endoplasmic reticulum (ER) stress as demonstrated by t...

the aims of the study were to investigate the effect of poly(ε -caprolactone) (pcl) and nano- sio2 within the thermoplastic starch (tps) blends on the rate and extent of starch enzymatic hydrolysis using enzymes α-amylase and amyloglucosidase. the results of this study have revealed that blends with nano-sio2 content at 6 wt% exhibited a significantly reduced rate and extent of starch hydrolysi...

We have studied the electron transport in SiO2(Co)/GaAs and SiO2(Co)/Si heterostructures, where the SiO2(Co) structure is the granular SiO2 film with Co nanoparticles. In SiO2(Co)/GaAs heterostructures giant magnetoresistance effect is observed. The effect has positive values, is expressed, when electrons are injected from the granular film into the GaAs semiconductor, and has the temperature-p...

Acute paraquat (PQ) poisoning is one of the most common forms of pesticide poisoning. Oxidative stress and inflammation are thought to be important mechanisms in PQ-induced acute lung injury (ALI). Selenium (Se) can scavenge intracellular free radicals directly or indirectly. In this study, we investigated whether porous Se@SiO2 nanospheres could alleviate oxidative stress and inflammation in P...

Background Methylprednisolone (MPS) is an important drug used in therapy of many diseases. However, osteonecrosis of the femoral head is a serious damage in the MPS treatment. Thus, it is imperative to develop new drugs to prevent the serious side effect of MPS. Methods The potential interferences Se@SiO2 nanocomposites may have to the therapeutic effect of methylprednisolone (MPS) were evalu...

In this paper, the optical properties of the multilayer rugate filter by structure of (HL) ^ 9Hhas been investigated. Here the reflection, optical density and electric field strength of designed filter by using four materials of Ta2O2, Nb2O5 and ZnS as the materials with high refractive indexandSiO2as a material with low refractive index are compared with each other. Finally, it is realized tha...

In this article, we have fabricated and studied a new multilayer structure Si-SiO2/SiNx by reactive magnetron sputtering. The comparison between SiO2 and SiNx host matrices in the optical properties of the multilayers is detailed. Structural analysis was made on the multilayer structures using Fourier transform infrared spectroscopy. The effect of specific annealing treatments on the optical pr...

The novel SiO2 net-like nanobelts have been successfully fabricated on Au-coated Si substrates by a simple thermal evaporation of CdS powder. The as-synthesized SiO2 nanostructures were characterized by using scanning electron microscope (SEM), transmission electron microscope (TEM) and energy dispersive spectroscopy (EDS), respectively. The as-grown SiO2 net-like nanobelts are rather uniformly...

This paper reports the inhibition efficiency of a family of polyaminoamide (PAMAM) STARBURST® dendrimers in colloidal SiO2 growth. PAMAMs of various generations (0.5, 1.5, 2.5 with –COOH termini, and 1, and 2 with –NH2 termini) were tested and compared to control samples. Superiority of the dendrimer inhibitors with –NH2 termini (maintaining∼380 ppm soluble SiO2 after 12 h) versus those with –C...