Abstract. The focus of the present study is the modified Buckley-Leverett (MBL) equation 1 describing two-phase flow in porous media. The MBL equation differs from the classical Buckley2 Leverett (BL) equation by including a balanced diffusive-dispersive combination. The dispersive term 3 is a third order mixed derivatives term, which models the dynamic effects in the pressure difference 4 betw...

The advent of functional MRI in the mid-1990s has catalyzed progress pertaining to scientific discoveries in neuroscience. With the prospect of elucidating the physiological aspect of the Blood Oxygenation Level Dependent (BOLD) effect we present a computational capillary-tissue system capable of mapping venous hemoglobin saturation- a marker of the BOLD hemodynamic response. Free and facilitat...

`gym-saturation` is an OpenAI Gym environment for reinforcement learning (RL) agents capable of proving theorems. Currently, only theorems written in a formal language the Thousands Problems Theorem Provers (TPTP) library clausal normal form (CNF) are supported. implements 'given clause' algorithm (similar to one used Vampire and E Prover). Being Python, was inspired by PyRes. In contrast monol...

Due to the lack of a robust temperature model and poor knowledge about influence law profile, it is still highly challenging interpret production profile vertical wells in layered gas reservoirs from distributed sensing (DTS) quantitatively. In this paper, coupled prediction for reservoir developed, considering several microthermal effects non-isothermal seepage. Based on theoretical simulation...

The contamination impact and the migration of contaminant into surrounding environment due to presence a spilled oil pipeline will cause significant damage natural ecosystem. For this reason, developing rapid response strategy that might include accurate predictions trajectories from numerical simulation modeling is decisive. This paper uses three-dimensional model based on high-resolution shoc...

Models were developed for prediction and interpretation of the observed steady-state axial dissolved oxygen concentration profiles in tall airlift bioreactors. The observed concentration profiles were non-linear because of a combination of hydrodynamic and mass transport factors. The profiles were influenced mainly by the liquid-phase axial dispersion coefficient, the volumetric overall gas–liq...

a periodic increase in blood pressure (bp) occurs during apneic episodes in patients with obstructive sleep apnea (osa). several factors including hypoxemia and an increase in heart rate (hr) were reported to be responsible for this increased bp. to examine the contribution of these two factors in increasing bp, 35 healthy male subjects (mean age±sd= 23.64±3.80) were studied in three experiment...

Circulating nucleic acids (CNAs) are under investigation as a liquid biopsy in cancer. However there is wide variation in blood processing and methods for isolation of circulating free DNA (cfDNA) and microRNAs (miRNAs). Here we compare the extraction efficiency and reproducibility of 4 commercially available kits for cfDNA and 3 for miRNA using spike-in of reference templates. We also compare ...

The pharmacokinetics of increasing doses of an intrarectal Cinchona alkaloid combination containing 96.1% quinine, 2.5% quinidine, 0.68% cinchonine, and 0.67% cinchonidine (Quinimax) was compared to that of parenteral regimens in 60 children with moderate malaria. Quinine exhibited a nonlinear pharmacokinetics, suggesting a saturation of rectal resorption. When early rejections appeared, blood ...

I. Reinhard,* C. Callegari, A. Conjusteau, K. K. Lehmann, and G. Scoles Department of Chemistry, Princeton University, Princeton, New Jersey 08544 (Received 18 February 1999) Purely rotational transitions of a molecule embedded in large 4He clusters have been detected for the first time. The saturation behavior shows that, in contrast to previous expectations, the microwave line profiles are do...