نتایج جستجو برای: sanguinarine

تعداد نتایج: 260  

Journal: :Antioxidants & redox signaling 2016
Elaine Lai-Han Leung Xing-Xing Fan Maria Pik Wong Zhi-Hong Jiang Zhong-Qiu Liu Xiao-Jun Yao Lin-Lin Lu Yan-Ling Zhou Li-Fong Yau Vicky Pui-Chi Tin Liang Liu

AIMS Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been developed to treat non-small cell lung cancer (NSCLC) patients with EGFR mutation, but TKI resistance is common. Almost half of the acquired resistance patients are due to additional T790M mutation on EGFR (EGFR(T790M)), thus overcoming TKI resistance is important. In this study, we aim to investigate the r...

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