Purpose: It has been reported that diffusion-weighted imaging (DWI) might be useful for characterizing head and neck tumors, suggesting that malignant tumors have a lower apparent diffusion coefficient (ADC) than benign tumors. However, it remains uncertain if ADC is useful for distinguishing between benign and malignant salivary gland tumors. This study was intended to evaluate the ADC of beni...

OBJECTIVE Mucoepidermoid carcinoma (MEC) is the most common primary malignancy of the salivary glands. Insulin-like growth factor-II mRNA-binding protein-3 (IMP3) is an important prognostic factor in some cancers and a tool that differentiates between benign and malignant pancreatic lesions. This study aimed to identify a relationship between the expression of IMP3 and the outcome of salivary g...

Introduction. Lymphoepithelioma-like carcinoma (LELC) of the salivary gland is a rare tumor. Currently, surgery with or without radiotherapy is the recommended treatment for all salivary gland carcinomas. However, in contrast to other high-grade salivary gland carcinomas, LELCs are considered radiosensitive. There are only a few published reports of radiotherapy alone for the treatment of saliv...

Pleomorphic adenoma or benign mixed tumor is the most common salivary gland tumor. It is most frequently located in the parotid gland, and is considered to be a benign neoplasm accounting for 70-80% of all benign tumors of the salivary glands [1]. Benign metastasizing pleomorphic adenoma is extremely rare, with only a handful of cases described. We report a case of a histologically benign mixed...

Distant metastases from salivary gland tumors are considered infrequent: the incidence of distant metastases ranges from 24% to 61% according to different histotypes and to the site of the primary mass. The most common site of distant metastases due to salivary gland malignancies is the lung. From the pathology point of view, cytokeratins (CK) are important differentiation markers in salivary g...

Pleomorphic adenoma (PA), the most common salivary gland tumor, accounts for 54 to 65% of all salivary gland neoplasias and 80% of the benign salivary gland tumors. It most frequently affects the parotid gland, followed by the submandibular and the minor salivary glands. Microscopically, mucous, sebaceous, oncocytic and squamous metaplasia, sometimes with the formation of keratin pearls, may be...

INTRODUCTION Cyfra 21 is a serum-soluble fragment of cytokeratin19. Increased Cyfra 21 serum levels and their benefit as a tumor marker have been shown in some malignancies. This study aimed to evaluate the serum levels of Cyfra 21 in patients with benign and malignant salivary gland tumors. MATERIALS AND METHODS In this cross-sectional study, the serum level of Cyfra 21 in 44 patients with m...

introduction sialolithiasis is the most common disease of salivary glands. sialography is particularly important for the assessment of the outflow tract and in diagnosing obstructive salivary gland lesions including calculi. case presentation we report on a 38-year-old female with sialolithiasis whom had wharton’s duct perforation, complicating the sialography. she was treated conservatively wi...

salivary gland involvement is one of the radioiodine therapy complications. salivary gland scintigraphy in quantitative mode can accurately evaluate salivary gland function. methods: salivary gland scintigraphy was performed with tc-99m pertechnetate, at the time of iodine therapy as a basic study and then 3 weeks and 3 months afterwards. ejection fraction (ef) of parotid and submandibular glan...