salivary gland tumors are rare in children and, when they do arise, they mainly affect the major salivary glands. minor salivary gland tumors are rare in children and are responsible for less than 10% of the cases. pleomorphic adenoma is the most common tumor of the salivary glands. the most common sites of pleomorphic adenoma of the minor salivary glands are the palates, followed by the lips a...

introduction: chronic sclerosing sialadenitis is a relatively uncommon disorder of the salivary gland. because of its clinical similarity to a salivary gland neoplasm, this condition has been known as kuttner tumor and is classified as a tumorlike lesion. case report: this is the first reported case of bilateral kuttner tumor of the submandibular glands in iran. it was initially diagnosed as a ...

INTRODUCTION Natural killer (NK) cells, of which CD56 is a specific marker, play an important role in host defense against tumors. Cancer stem cells, of which aldehyde dehydrogenase isoform 1 (ALDH1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. We aimed to evaluate the expression of ALDH1 and CD56 in common salivary gl...

Background: Iodine-131 (I-131) is an effective treatment for differentiated thyroid carcinomas (DTC) after surgery. Salivary and lacrimal gland dysfunction has been described in patients receiving high doses of 1-131 due to radiation damage to salivary and lacrimal glands. Objective: This prospective study was conducted to determine the short term effect of oral 1-131 therapy administered to th...

UNLABELLED Salivary gland dysfunction is one of the common side effects of high-dose radioiodine therapy for thyroid cancer. The purpose of this study was to determine whether an early start of sucking lemon candy decreases salivary gland injury after radioiodine therapy. METHODS The incidence of the side effects of radioiodine therapy on the salivary glands was prospectively and longitudinal...

OBJECTIVE This study proposes a revision of the literature on the current techniques employed in salivary gland biopsy. METHODS A systematic review of the literature between January 1990 and January 2010 was conducted using MEDLINE, Embase and the Cochrane Central Register of Controlled Trials. The search terms were: 'biopsy AND parotid AND Sjögren'; 'biopsy AND sublingual salivary gland AND ...

Epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here a case of 58-year-old female presented with left cheek swelling of one-year duration. CT scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. Histological examin...

Hemangiomas are defined as soft tissue lesions in the maxillofacial or oral region. Hemangiomas of salivary glands constitute 30% of the non-epithelial tumors in major salivary glands.  Benign tumors in salivary glands are located 85% in parotid gland and 13% in submandibular gland. We present a case of submandibular hemangioma in an infant patient that had some complications and a challenging ...

BACKGROUND Non-obese diabetic (NOD) mice exhibit autoimmune diabetes and Sjögren's-like syndrome. OBJECTIVE To test whether a treatment that reverses end-stage diabetes in the NOD mouse would affect their Sjögren's-like syndrome. METHODS NOD mice have a proteasome defect. Improperly selected naive T cells escape, but can be killed by reintroducing major histocompatibility complex class I se...

Following radiotherapy, many patients with osteoradionecrosis suffer from xerostomia, thereby decreasing their quality of life. Patients can develop problems with speech, eating, increased dental caries, dysphagia, fractured dentition, chronic refractory osteomyelitis and osteoradionecrosis. Symptoms associated with salivary gland dysfunction can be severe enough that patients terminate the cou...