saffron (crocus sativus l.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. the pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. additionally, other lines of studies have found toxicological effects of saffron.  ho...

Hanseniaspora vineae and opuntiae are apiculate yeasts normally found on the skins of ripe grapes at beginning alcoholic fermentation. Several studies have reported that these species can provide interesting sensory characteristics to wine by contributing high levels acetate esters increase mouthfeel body wines. The present work aims evaluate use two sequentially with Saccharomyces cerevisiae i...

Anxiety disorders and schizophrenia are common public health issues. The dried stigma of the plant Crocus sativus L., (C. sativus) commonly known as saffron are used in folk medicine for various purposes. Several lines of evidence suggest that C. sativus, crocins and safranal are implicated in anxiety and schizophrenia. Here, I intend to critically review advances in research of these emerging ...

OBJECTIVES The aim of the present study was to investigate immunotoxic effect of safranal (SAF), a main component of Crocus sativus essential oil, using Balb/c mice. MATERIALS AND METHODS SAF was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. Hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (DTH) res...

objective(s):this study was designed to evaluate the cardioprotective effect of crocus sativus l. (saffron)aqueous extract and safranal, the major constituent of the essential oil of saffron, on lipid peroxidation, biochemical parameters and histopathological findings in isoproterenol (iso)-induced myocardial infarction in wistar rats. materials and methods:the saffron extract (20, 40, 80 and 1...