The present study investigated the cytogenetic and testicular damage induced by the antiepileptic drug, sodium valporate (SVP) in albino rats and the effect of saffron aqueous extracts. Treating rats with SVP caused a significant increase in the chromosomal aberrations either structural or numerical and decreased the mitotic index. Besides, animals administered SVP showed DNA damage appeared in...

The terms senescence and programmed cell death (PCD) have led to some confusion. Senescence as visibly observed in, for example, leaf yellowing and petal wilting, has often been taken to be synonymous with the programmed death of the constituent cells. PCD also obviously refers to cells, which show a programme leading to their death. Some scientists noted that leaf yellowing, if it has not gone...

Depressive disorders are very common in clinical practice, with approximately 11.3 of all adults afflicted during any a year. Saffron is the world's most expensive spice and apart from its traditional value as a food additive, recent studies indicate several therapeutic effects for saffron. It is used for depression in Persian traditional medicine. Our objective was to compare the efficacy of h...

Introduction: Cognitive dysfunction is recognized as a significant feature of multiple sclerosis (MS). Oxidative stress plays an important role in the pathogenesis of MS. Toxic demyelination by ethidium bromide (EB) is one of the common methods for induction of MS, which leads to neuronal death by production of free radicals and enhancement of oxidative stress burden. According to previous p...

current therapies for breast cancer are often limited by short-term efficacy due to the emergence of drug resistance. there has been increased interest in the use of naturally occurring compounds with chemopreventive and chemotherapeutic effects in the treatment of cancers. saffron, dry stigmas crocus sativus l., used in iran as a spice, is known for its anticancer properties. in this study, th...

in this paper the separation of saffron stigma from stamen and petal in a vertical wind tunnel has been evaluated. a wind tunnel with adjustable speed of 0.1 m s-1 intervals has been developed and used for the experiments. floating velocities of flower components (petal, stigma and stamen) were measured at one, eight, 38 and 60 hours after harvesting. subsequently, the separation was tested by ...

saffron flower (crocus sativus) is one of the most precious spices in the world. in this respect, thesaffron style samples were gathered from the farms of torbat-heidariyeh located in south khorasanprovince during one year and their preparation was performed based on the common manufacturingstandards. then, in order to considering the international and national standards for saffron and spicese...