Sacrococcygeal teratomas have tissues derived from ectoderm, mesoderm, and endoderm.2 Although their embryonic origin is still uncertain, they are believed to arise early in gestation (at around the late second or early third week) from the totipotential cells of Hensen's node (also called the primitive knot), a remnant of the primitive streak in the coccygeal region.5-7 The primitive streak ap...

Individuals with Down syndrome (DS) have a unique profile of neoplasms, with a higher incidence of leukemias and a lower incidence of solid tumors than seen in the general population. We recently encountered two cases of infants with DS with retroperitoneal teratoma. After reviewing the literature on teratomas in DS, we found that the incidence of retroperitoneal teratomas was higher and the in...

and Kendall, 1966) as well as a rise and alteration in plasma lipids. In addition, a decrease in fibrinolysis may be present (Cotton, 1967). Hypovolaemia is a usual finding in the nephrotic syndrome, and may be made worse by diuretic therapy. The increase in haematocrit, the vaso-constriction, and sluggish circulation tend to increase the likelihood of intravascular coagulation. Coagulation is ...