ObjectiveScoping review on IgE-mediated cow’s milk allergy prevention.Data SourcesLiterature search of PubMed database and gray literature.Study SelectionsPeer-reviewed relevant observational randomized controlled studies in the pediatric population English language were selected reviewed.ResultsThere is increasing literature supporting role early ongoing ingestion prevention allergy. The a pre...

background: diagnosis of food allergy is difficult in children. food allergies are diagnosed using several methods that include medical histories, clinical examinations, skin prick and serum-specific immunoglobulin e (ige) tests, radio-allergosorbent test (rast), food challenge, and supervised elimination diets. in this study we evaluated allergies to cow's milk, egg, peanut, and fish in c...

Tagatose is a new food ingredient being used as a reduced-calorie sweetener in foods and beverages. Tagatose is a six-carbon ketose sugar found naturally in some dairy products and in tropical date trees. As tagatose is incompletely absorbed, it provides only 1.5 cal/g as contrary to 4 cal/g for sucrose. Tagatose has approximately the same sweetness as sucrose. Recently, a manufacturing process...

BACKGROUND The impact of maternal ingestion of peanut during pregnancy and lactation on an offspring's risk for peanut allergy is under debate. OBJECTIVE To investigate the influence of maternal dietary peanut exposure and breast milk on an offspring's allergy risk. METHODS Preconceptionally peanut-exposed C3H/HeJ females were either fed or not fed peanut during pregnancy and lactation. The...

Intestinal biopsies were performed in children suffering from coeliac and other diseases and were stained by the 'astra-blau' method for visualising granulated mast cells. The density of granulated mast cells (per microscopical field) in treated coeliac disease and in 3 control groups (patients suffering from milk allergy, failure to thrive, or protracted diarrhoea) was 15--18 cells per microsc...

According to the position paper from the European Academy for Allergy and Clinical Immunology (EAACI) “food allergy” summarizes immune-mediated, non-toxic adverse reactions to foods (Figure 1)(Bruijnzeel-Koomen et al., 1995). The most common form of food allergy is mediated by immunoglobulin (Ig)E antibodies and reflects an immediatetype ("Type 1 hypersensitivity") reaction, i.e. acute onset of...

Cow’s milk, egg, wheat, soy, peanut, and fish account for about 90% of the food allergies but there are considerable differences from one country to another. Milk allergy is among the best characterized food allergies, particularly in infants and small children. Only part of the children with early allergy to cow’s milk grow into shool-age with milk allergy but those that do often have severe s...

OBJECTIVE This study aimed to evaluate the adverse effects of extensively hydrolyzed milk formula on growth in infants and toddlers. METHODS Prospectively, 45 infants and toddlers with a positive history of cow's milk allergy confirmed by positive skin prick test and high IgE levels for either alpha-lactalbumin, beta-lactoglobulin, or casein and positive single-blind food challenge received e...

Background The EC-directive 2006/141/E requires objective and scientifically verified data to claim hypoallergenicity of hydrolysed formulae. However, no validated animal models are currently available to assess the residual sensitising capacity, although guinea pig assays are frequently used. This study is part of a multi-phase project which aims to validate a recently developed mouse model to...