background and objective: alzheimer’s disease (ad) is a multifactorial disease with debilitating consequences and few therapeutic strategies exist for it. with regard to antioxidant capacity and anti-β-amyloid polymerization potential of ellagic acid, this study was conducted to evaluate the effect of this substance on enhanced acetylcholinesterase reactivity in an experimental model of alzheim...

diffuse hepatic inltration is an unusual form of hodgkin's disease (hd). its manifestation as progressive hepatitis or with hepatic failure is even rarer and can be difcult to diagnose. we aim to describe an unusual case of liver failure due to hd. a middle-aged woman with a 10 month history of daily febrile episodes, constitutional symptoms and strikingly high levels of serum ferritin was admi...

alzheimer's disease (ad), a common and debilitating neurodegenerative disorder, affect more than 65 million individuals throughout the world. this disability plays a crucial role in daily activities such as driving. several studies have investigated the relationship between cognitive functions and driving safety. the current study revises the literature on the relation between road safety ...

parkinson`s disease (pd) is the second most common neurodegenerative disorder after alzheimer`s disease. it is a chronic and progressive disease, and mostly afflicts elderlies. pd starts with sudden onsets and the exact cause of the disease is still unknown, however there are some early symptoms that can help us to diagnose the disease and ameliorate its effects. pd is a multi-factorial disease...

alzheimer's disease (ad) is considered as the greatest thread to adults aged 65 and older. it stands as the most common cause of dementia, the prevalence of which is around 24 million worldwide. ad is a progressive and degenerative disorder that combats the neurons, leading to impairment of different cognitive functions. ad is characterized by an accumulation of two factors normally presen...

Introduction:Brain imaging with F-18 fluorodeoxyglucose (18F-FDG) positron ‎emission tomography or Tc-99m hexamethylpropyleneamine oxime (‎99mTc-HMPAO) SPECT is widely used for the evaluation of Alzheimer's ‎dementia (AD); we aim to assess superiority of one method over the ‎other. Methods: Twenty four patients with clinical diagnosi...

this report is a brief presentation of one case of oilier's disease. ollier's disease (multiple enchondromata) patients have widespread involvement of the skeleton, especially the hands the lesions are detected because of bone pain or deformity. virtually all cases have been sporadic. roentgenographically, the lesions may be detectable in early infancy as clear, homogeneous, oval lesi...

background: marjolin's ulcer is a rare, aggressive condition that arises on chronic skin lesions and diseases. in this article, we will report 83 cases of this disease. methods: retrospectively, we retrieved 83 records of patients with cancer arising from chronic skin conditions. data concerning demography, type of original skin insult, time interval between original lesion and cancer, can...

abstract   background: dupuytren's disease is a fibroproliferative disorder of the palmar fascia   that can result in disabling contractures of the digits. when function is impeded or deformity is disabling, surgical intervention can be considered, wherein a major problem is recurrence ( reported up to 74%). although, the disease occurs predominantly in men of northern european, there are ...

we present a 19-year-old patient with hematologic and neurologic manifestations associated with wilson’s disease. idiopathic thrombocytopenia was diagnosed in october 2009. bone marrow aspiration was normal. gradually her neurologic and psychiatric symptoms emerged, dysarthria, writing apraxia, learning difficulties, emotionalism and eventually dystonia of hands. the serum ceruloplasmin was low...